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Zamani, E., Ksantini, N., Sheehy, G., Ember, K. J. I., Baloukas, B., Zabeida, O., Trang, T., Mahfoud, M., Sapieha, J.-E., Martinu, L., & Leblond, F. (2024). Spectral effects and enhancement quantification in healthy human saliva with surface-enhanced Raman spectroscopy using silver nanopillar substrates. Lasers in Surgery and Medicine, 56(2), 206-217. Disponible
Ember, K., Dallaire, F., Plante, A., Sheehy, G., Guiot, M.-C., Agarwal, R., Yadav, R., Douet, A., Selb, J., Tremblay, J. P., Dupuis, A., Marple, E., Urmey, K., Rizea, C., Harb, A., McCarthy, L., Schupper, A., Umphlett, M., Tsankova, N., ... Petrecca, K. (2024). In situ brain tumor detection using a Raman spectroscopy system—results of a multicenter study. Scientific Reports, 14, 14 (12 pages). Lien externe
David, S., Tavera, H., Trang, T., Dallaire, F., Daoust, F., Tremblay, F., Richer, L., Meterissian, S., & Leblond, F. (2024). Macroscopic inelastic scattering imaging using a hyperspectral line-scanning system identifies invasive breast cancer in lumpectomy and mastectomy specimens. Journal of Biomedical Optics, 29(6), 16 pages. Lien externe
Grajales, D., Le, W. T., Tran, T., David, S., Dallaire, F., Ember, K., Leblond, F., Menard, C., & Kadoury, S. (2024). Robot-assisted biopsy sampling for online Raman spectroscopy cancer confirmation in the operating room. International Journal of Computer Assisted Radiology and Surgery, 9-9. Lien externe
David, S., Ksantini, N., Dallaire, F., Ember, K., Daoust, F., Sheehy, G., Hadjipanayis, C. G., Petrecca, K., Wilson, B. C., & Leblond, F. (2024). Toward noncontact macroscopic imaging of multiple cancers using multi-spectral inelastic scattering detection. Journal of Biophotonics, 2024000087 (7 pages). Lien externe
Daoust, F., Tavera, H., Dallaire, F., Orsini, P., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (2023). A clinical Raman spectroscopy imaging system and safety requirements for in situ intraoperative tissue characterization. Analyst, 148(9), 1991-2001. Lien externe
Bido, A. T., Ember, K. J. I., Trudel, D., Durand, M., Leblond, F., & Brolo, A. G. (2023). Detection of SARS-CoV-2 in saliva by a low-cost LSPR-based sensor. Analytical Methods, 32(32), 3955-3966. Lien externe
David, S., Tran, T., Dallaire, F., Sheehy, G., Azzi, F., Trudel, D., Tremblay, F., Omeroglu, A., Leblond, F., & Meterissian, S. (2023). In situ Raman spectroscopy and machine learning unveil biomolecular alterations in invasive breast cancer. Journal of Biomedical Optics, 28(3), 036009 (18 pages). Lien externe
Sheehy, G., Picot, F., Dallaire, F., Ember, K., Nguyen, T., Petrecca, K., Trudel, D., & Leblond, F. (2023). Open-sourced Raman spectroscopy data processing package implementing a baseline removal algorithm validated from multiple datasets acquired in human tissue and biofluids. Journal of Biomedical Optics, 28(2), 025002 (20 pages). Lien externe
Kosik, I., Dallaire, F., Pires, L., Tran, T., Leblond, F., & Wilson, B. (2023). Preclinical evaluation of Raman spectroscopy for pedicular screw insertion surgical guidance in a porcine spine model. Journal of Biomedical Optics, 28(5), 057003 (15 pages). Lien externe
Gagnon, J. R., Allen, C. H., Trudel, D., Leblond, F., Stys, P. K., Brideau, C., & Murugkar, S. (2023). Spectral focusing-based stimulated Raman scattering microscopy using compact glass blocks for adjustable dispersion. Biomedical Optics Express, 14(6), 2510-2522. Lien externe
Leblond, F., Dallaire, F., Tran, T., Yadav, R., Aubertin, K., Goudie, E., Romeo, P., Kent, C., Leduc, C., & Liberman, M. (2023). Subsecond lung cancer detection within a heterogeneous background of normal and benign tissue using single-point Raman spectroscopy. Journal of Biomedical Optics, 28(9), 090501 (8 pages). Lien externe
Blais-Ouellette, S., Rooney, D., Heller, D. A., Roxbury, D., Leblond, F., & Akbarzadeh, A. (2022). (Invited) Advances in Swir In Vivo Fluorescence Imaging Instrumentation. Meeting abstracts, MA2022-01(8), 676-676. Lien externe
Ember, K., Daoust, F., Mahfoud, M., Dallaire, F., Ahmad, E. Z., Tran, T., Plante, A., Diop, M.-K., Nguyen, T., St-Georges-Robillard, A., Ksantini, N., Lanthier, J., Filiatrault, A., Sheehy, G., Beaudoin, G., Quach, C., Trudel, D., & Leblond, F. (2022). Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning. Journal of Biomedical Optics, 27(2), 025002 (24 pages). Disponible
Picot, F., Shams, R., Dallaire, F., Sheehy, G., Trang, T., Grajales, D., Birlea, M., Trudel, D., Menard, C., Kadoury, S., & Leblond, F. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 1: Raman spectroscopy fiber-optics system and in situ tissue characterization. Journal of Biomedical Optics, 27(9), 095003 (14 pages). Lien externe
Lopera, D. O. G., Picot, F., Shams, R., Dallaire, F., Sheehy, G., Alley, S., Barkati, M., Delouya, G., Carrier, J.-F., Birlea, M., Trudel, D., Leblond, F., Menard, C., & Kadoury, S. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model combining spectral and MRI-radiomics features. Journal of Biomedical Optics, 27(9), 095004 (16 pages). Lien externe
Laurence, A., Toffa, D. H., Peng, K., Robert, M., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2022). Multispectral intraoperative imaging for the detection of the hemodynamic response to interictal epileptiform discharges. Biomedical Optics Express, 13(12), 6245-6257. Lien externe
David, S., Plante, A., Dallaire, F., Tremblay, J.-P., Sheehy, G., Macdonald, E., Forrest, L., Daneshmand, M., Trudel, D., Wilson, B. C., Hopkins, L., Murugkar, S., Vanderhyden, B., & Leblond, F. (2022). Multispectral label-free Raman spectroscopy can detect ovarian and endometrial cancer with high accuracy. Journal of Biophotonics, 15(2), 10 pages. Lien externe
Ciobanu, C., Ember, K. J. I., Nyíri, B. J., Rajan, S., Chauhan, V., Leblond, F., & Murugkar, S. (2022). Potential of Raman Spectroscopy for Blood-Based Biopsy. IEEE Instrumentation & Measurement Magazine, 25(1), 62-68. Lien externe
Ksantini, N., Veilleux, I., de Denus-Baillargeon, M.-M., Orsini, P., Dicaire, I., Lecourt, J.-B., Gognau, A., Hernandez, Y., Baylon, A., Massabki, M., Lesage, F., & Leblond, F. (2022). Time-gated interferometric detection increases Raman scattering to fluorescence signal ratio in biological samples. Journal of Biophotonics, 15(1), 6 pages. Lien externe
Plante, A., Dallaire, F., Grosset, A.-A., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., Van Der Kwast, T., ... Leblond, F. (2021). Dimensional reduction based on peak fitting of Raman micro spectroscopy data improves detection of prostate cancer in tissue specimens. Journal of Biomedical Optics, 26(11), 14 pages. Lien externe
Daoust, F., Nguyen, T., Orsini, P., Bismuth, J., de Denus-Baillargeon, M.-M., Veilleux, I., Wetter, A., McKoy, P., Dicaire, I., Massabki, M., Petrecca, K., & Leblond, F. (2021). Handheld macroscopic Raman spectroscopy imaging instrument for machine-learning-based molecular tissue margins characterization. Journal of Biomedical Optics, 26(2), 18 pages. Lien externe
Shabestri, B., Anastasio, M. A., Fei, B., & Leblond, F. (2021). Special Series Guest Editorial: Artificial Intelligence and Machine Learning in Biomedical Optics. Journal of Biomedical Optics, 26(5), 4 pages. Lien externe
Akbarzadeh, A., Edjlali, E., Sheehy, G., Selb, J., Agarwal, R., Weber, J., & Leblond, F. (2020). Experimental validation of a spectroscopic Monte Carlo light transport simulation technique and Raman scattering depth sensing analysis in biological tissue. Journal of Biomedical Optics, 25(10), 105002 (19 pages). Disponible
Picot, F., Daoust, F., Sheehy, G., Dallaire, F., Chaikho, L., Bégin, T., Kadoury, S., & Leblond, F. (2020). Data consistency and classification model transferability across biomedical Raman spectroscopy systems. Translational Biophotonics, 3(1), 1-11. Disponible
Dallaire, F., Picot, F., Tremblay, J.-P., Sheehy, G., Lemoine, É., Agarwal, R., Kadoury, S., Trudel, D., Lesage, F., Petrecca, K., & Leblond, F. (2020). Quantitative spectral quality assessment technique validated using intraoperative in vivo Raman spectroscopy measurements. Journal of Biomedical Optics, 25(4). Disponible
Beaulieu, E., Laurence, A., Birlea, M., Sheehy, G., Angulo-Rodriguez, L., Latour, M., Albadine, R., Saad, F., Trudel, D., & Leblond, F. (2020). Wide-field optical spectroscopy system integrating reflectance and spatial frequency domain imaging to measure attenuation-corrected intrinsic tissue fluorescence in radical prostatectomy specimens. Biomedical Optics Express, 11(4), 2052-2072. Disponible
Grosset, A.-A., Dallaire, F., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., van der Kwast, T., Orain, M., ... Trudel, D. (2020). Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation. Plos Medicine, 17(8), e1003281 (20 pages). Lien externe
Laurence, A., Bouthillier, A., Robert, M., Nguyen, D. K., & Leblond, F. (2020). Multispectral diffuse reflectance can discriminate blood vessels and bleeding during neurosurgery based on low-frequency hemodynamics. Journal of Biomedical Optics, 25(11), 10 pages. Lien externe
Shams, R., Picot, F., Grajales, D., Sheehy, G., Dallaire, F., Birlea, M., Saad, F., Trudel, D., Menard, C., Leblond, F., & Kadoury, S. (2020). Pre-clinical evaluation of an image-guided in-situ Raman spectroscopy navigation system for targeted prostate cancer interventions. International Journal of Computer Assisted Radiology and Surgery, 15(5), 867-876. Lien externe
Depaoli, D., Lemoine, É., Ember, K., Parent, M., Prud'Homme, M., Cantin, L., Petrecca, K., Leblond, F., & Cote, D. C. (2020). Rise of Raman spectroscopy in neurosurgery: A review. Journal of Biomedical Optics, 25(5), 36 pages. Lien externe
Picot, F., Goyette, A., Obaid, S., Desroches, J., Lessard, S., Tremblay, M.-A., Strupler, M., Wilson, B., Petrecca, K., Soulez, G., & Leblond, F. (2019). Interstitial imaging with multiple diffusive reflectance spectroscopy projections for in vivo blood vessels detection during brain needle biopsy procedures. Neurophotonics, 6(2), 025003 (8 pages). Disponible
St-Georges-Robillard, A., Cahuzac, M., Péant, B., Fleury, H., Lateef, M. A., Ricard, A., Sauriol, A., Leblond, F., Mes-Masson, A.-M., & Gervais, T. (2019). Long-term fluorescence hyperspectral imaging of on-chip treated co-culture tumour spheroids to follow clonal evolution. Integrative Biology, 11(4), 130-141. Disponible
Pinto, M., Zorn, K. C., Tremblay, J.-P., Desroches, J., Dallaire, F., Aubertin, K., Marple, E., Kent, C., Leblond, F., Trudel, D., & Lesage, F. (2019). Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures. Journal of Biomedical Optics, 24(2), 025001 (10 pages). Disponible
Desroches, J., Lemoine, É., Pinto, M., Marple, E., Urmey, K., Diaz, R., Guiot, M.-C., Wilson, B. C., Petrecca, K., & Leblond, F. (2019). Development and first in-human use of a Raman spectroscopy guidance system integrated with a brain biopsy needle. Journal of Biophotonics, 12(3), e201800396 (7 pages). Lien externe
Lemoine, É., Dallaire, F., Yadav, R., Agarwal, R., Kadoury, S., Trudel, D., Guiot, M.-C., Petrecca, K., & Leblond, F. (2019). Feature engineering applied to intraoperative in vivo Raman spectroscopy sheds light on molecular processes in brain cancer: a retrospective study of 65 patients. Analyst, 144(22), 6517-6532. Lien externe
Sibai, M., Wirth, D. J., Leblond, F., Roberts, D. W., Paulsen, K. D., & Wilson, B. C. (2019). Quantitative subsurface spatial frequency-domain fluorescence imaging for enhanced glioma resection. Journal of Biophotonics, 12(5), 6 pages. Lien externe
St-Georges-Robillard, A., Masse, M., Cahuzac, M., Strupler, M., Patra, B., Orimoto, A. M., Kendall-Dupont, J., Péant, B., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (2018). Fluorescence hyperspectral imaging for live monitoring of multiple spheroids in microfluidic chips. Analyst, 143(16), 3829-3840. Disponible
Desroches, J., Jermyn, M., Pinto, M., Picot, F., Tremblay, M.-A., Obaid, S., Marple, E., Urmey, K., Trudel, D., Soulez, G., Guiot, M.-C., Wilson, B. C., Petrecca, K., & Leblond, F. (2018). A new method using Raman spectroscopy for in vivo targeted brain cancer tissue biopsy. Scientific Reports, 8(1). Disponible
Wilson, B. C., Jermyn, M., & Leblond, F. (2018). Challenges and opportunities in clinical translation of biomedical optical spectroscopy and imaging. Journal of Biomedical Optics, 23(3), 13 pages. Lien externe
Aubertin, K., Desroches, J., Jermyn, M., Trinh, V. Q., Saad, F., Trudel, D., & Leblond, F. (2018). Combining high wavenumber and fingerprint raman spectroscopy for the detection of prostate cancer during radical prostatectomy. Biomedical Optics Express, 9(9), 4294-4305. Lien externe
St-Arnaud, K., Aubertin, K., Strupler, M., Madore, W.-J., Grosset, A.-A., Petrecca, K., Trudel, D., & Leblond, F. (2018). Development and characterization of a handheld hyperspectral Raman imaging probe system for molecular characterization of tissue on mesoscopic scales. Medical Physics, 45(1), 328-339. Lien externe
Aubertin, K., Quoc-Trinh, V., Jermyn, M., Baksic, P., Grosset, A.-A., Desroches, J., St-Arnaud, K., Birlea, M., Vladoiu, M. C., Latour, M., Albadine, R., Saad, F., Leblond, F., & Trudel, D. (2018). Mesoscopic characterization of prostate cancer using Raman spectroscopy : potential for diagnostics and therapeutics. BJU International, 122(2), 326-336. Lien externe
Roberts, D. W., Olson, J. D., Evans, L. T., Kolste, K. K., Kanick, S. C., Fan, X., Bravo, J. J., Wilson, B. C., Leblond, F., Marois, M., & Paulsen, K. D. (2018). Red-light excitation of protoporphyrin IX fluorescence for subsurface tumor detection. Journal of Neurosurgery, 128(6), 1690-1697. Lien externe
St-Pierre, C., Madore, W.-J., De Montigny, É., Trudel, D., Boudoux, C., Godbout, N., Mes-Masson, A.-M., Rahimi, K., & Leblond, F. (2017). Dimension reduction technique using a multilayered descriptor for high-precision classification of ovarian cancer tissue using optical coherence tomography: a feasibility study. Journal of Medical Imaging, 4(4), 13 pages. Lien externe
Wirth, D., Kolste, K., Kanick, S., Roberts, D. W., Leblond, F., & Paulsen, K. D. (2017). Fluorescence depth estimation from wide-field optical imaging data for guiding brain tumor resection: A multi-inclusion phantom study. Biomedical Optics Express, 8(8), 3656-3670. Lien externe
Jermyn, M., Mercier, J., Aubertin, K., Desroches, J., Urmey, K., Karamchandiani, J., Marple, E., Guiot, M.-C., Leblond, F., & Petrecca, K. (2017). Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy. Cancer Research, 77(14), 3942-3950. Lien externe
Gough, K. M., & Leblond, F. (2017). Optical diagnosis: Highlighting the clinical applications of vibrational spectroscopy. Analyst, 142(8), 1177-1178. Lien externe
Sibai, M., Fisher, C., Veilleux, I., Elliott, J. T., Leblond, F., Roberts, D. W., & Wilson, B. C. (2017). Preclinical evaluation of spatial frequency domain-enabled wide-field quantitative imaging for enhanced glioma resection. Journal of Biomedical Optics, 22(7), 10 pages. Lien externe
Desroches, J., Laurence, A., Jermyn, M., Pinto, M., Tremblay, M.-A., Petrecca, K., & Leblond, F. (2017). Raman spectroscopy in microsurgery: impact of operating microscope illumination sources on data quality and tissue classification. Analyst, 142(8), 1185-1191. Lien externe
Pichette, J., Laurence, A., Angulo, L., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2016). Intraoperative video-rate hemodynamic response assessment in human cortex using snapshot hyperspectral optical imaging. Neurophotonics, 3(4). Lien externe
Astolfi, M., St-Georges-Robillard, A., Leblond, F., Mes-Masson, A.-M., & Gervais, T. (2016). Microfluidics and spectroscopic imaging for personalized medicine in ovarian cancer. SPIE Newsroom. Lien externe
Jermyn, M., Desroches, J., Mercier, J., Tremblay, M.-A., St-Arnaud, K., Guiot, M.-C., Petrecca, K., & Leblond, F. (2016). Neural networks improve brain cancer detection with Raman spectroscopy in the presence of operating room light artifacts. Journal of Biomedical Optics, 21(9). Lien externe
Jermyn, M., Desroches, J., Mercier, J., St-Arnaud, K., Guiot, M.-C., Leblond, F., & Petrecca, K. (2016). Raman spectroscopy detects distant invasive brain cancer cells centimeters beyond MRI capability in humans. Biomedical Optics Express, 7(12), 5129-5137. Lien externe
Jermyn, M., Desroches, J., Aubertin, K., St-Arnaud, K., Madore, W.-J., De Montigny, E., Guiot, M.-C., Trudel, D., Wilson, B. C., Petrecca, K., & Leblond, F. (2016). A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology. Physics in Medicine and Biology, 61(23), R370-R400. Lien externe
St-Arnaud, K., Aubertin, K., Strupler, M., Jermyn, M., Petrecca, K., Trudel, D., & Leblond, F. (2016). Wide-field spontaneous Raman spectroscopy imaging system for biological tissue interrogation. Optics Letters, 41(20), 4692-4695. Lien externe
Desroches, J., Jermyn, M., Mok, K., Lemieux-Leduc, C., Mercier, J., St-Arnaud, K., Urmey, K., Guiot, M.-C., Marple, E., Petrecca, K., & Leblond, F. (2015). Characterization of a Raman spectroscopy probe system for intraoperative brain tissue classification. Biomedical Optics Express, 6(7), 2380-2397. Lien externe
Jermyn, M., Gosselin, Y., Valdes, P. A., Sibai, M., Kolste, K., Mercier, J., Angulo, L., Roberts, D. W., Paulsen, K. D., Petrecca, K., Daigle, O., Wilson, B. C., & Leblond, F. (2015). Improved sensitivity to fluorescence for cancer detection in wide-field image-guided neurosurgery. Biomedical Optics Express, 6(12), 5063-5074. Lien externe
Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Bernstein, L., Guiot, M. C., Petrecca, K., & Leblond, F. (2015). Intraoperative brain cancer detection with Raman spectroscopy in humans. Science Translational Medicine, 7(274), 9-9. Lien externe
Leblond, F., Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Guiot, M.-C., & Petrecca, K. (2015). Intraoperative detection of cancerous brain tissue using Raman spectroscopy. SPIE Newsroom. Lien externe
Kolste, K. K., Kanick, S. C., Valdés, P. A., Jermyn, M., Wilson, B. C., Roberts, D. W., Paulsen, K. D., & Leblond, F. (2015). Macroscopic optical imaging technique for wide-field estimation of fluorescence depth in optically turbid media for application in brain tumor surgical guidance. Journal of Biomedical Optics, 20(2), 026002 (8 pages). Lien externe
Jermyn, M., Kolste, K., Pichette, J., Sheehy, G., Angulo-Rodriguez, L., Paulsen, K. D., Roberts, D. W., Wilson, B. C., Petrecca, K., & Leblond, F. (2015). Macroscopic-imaging technique for subsurface quantification of near-infrared markers during surgery. Journal of Biomedical Optics, 20(3). Lien externe
Valdés, P. A., Jacobs, V., Harris, B. T., Wilson, B. C., Leblond, F., Paulsen, K. D., & Roberts, D. W. (2015). Quantitative fluorescence using 5-aminolevulinic acid-induced protoporphyrin IX biomarker as a surgical adjunct in low-grade glioma surgery. Journal of Neurosurgery, 123(3), 771-780. Lien externe
Sibai, M., Veilleux, I., Elliott, J. T., Leblond, F., & Wilson, B. C. (2015). Quantitative spatial frequency fluorescence imaging in the sub-diffusive domain for image-guided glioma resection. Biomedical Optics Express, 6(12), 4923-4933. Lien externe
Pichette, J., Goyette, A., Picot, F., Tremblay, M.-A., Soulez, G., Wilson, B. C., & Leblond, F. (2015). Sensitivity analysis aimed at blood vessels detection using interstitial optical tomography during brain needle biopsy procedures. Biomedical Optics Express, 6(11), 4238-4254. Lien externe
Goyette, A., Pichette, J., Tremblay, M.-A., Laurence, A., Jermyn, M., Mok, K., Paulsen, K. D., Roberts, D. W., Petrecca, K., Wilson, B. C., & Leblond, F. (2015). Sub-diffuse interstitial optical tomography to improve the safety of brain needle biopsies: a proof-of-concept study. Optics Letters, 40(2), 170-173. Lien externe
Valdes, P. A., Bekelis, K., Harris, B. T., Wilson, B. C., Leblond, F., Kim, A., Simmons, N. E., Erkmen, K., Paulsen, K. D., & Roberts, D. W. (2014). 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence in Meningioma: Qualitative and Quantitative Measurements In Vivo. Neurosurgery, 10(1), 74-82. Lien externe
Thouin, F., Leblond, F., Martel, R., Verhaegen, M., & Daigle, O. (2014). Ultra Fast Raman Hyperspectral Imaging using Bragg Tunable Filters and a High Performance Emccd Camera. Biophysical Journal, 106(2), 613A-613A. Lien externe
Tichauer, K. M., Holt, R. W., El-Ghussein, F., Davis, S. C., Samkoe, K. S., Gunn, J. R., Leblond, F., & Pogue, B. W. (2013). Dual-tracer background subtraction approach for fluorescent molecular tomography. Journal of Biomedical Optics, 18(1), 16003. Disponible
Holt, R. W., Leblond, F., & Pogue, B. W. (2013). Methodology to Optimize Detector Geometry in Fluorescence Tomography of Tissue Using the Minimized Curvature of the Summed Diffuse Sensitivity Projections. Journal of the Optical Society of America A: Optics Image Science and Vision, 30(8), 1613-1619. Lien externe
Roberts, D. W., Valdés, P. A., Harris, B. T., Hartov, A., Fan, X., Ji, S., Pogue, B. W., Leblond, F., Tosteson, T. D., Wilson, B. C., & Paulsen, K. D. (2012). Adjuncts for maximizing resection: 5-aminolevuinic acid. Clinical Neurosurgery, 59(Supplement), 75-78. Lien externe
Basevi, H. R. A., Tichauer, K. M., Leblond, F., Pogue, B. W., Dehghani, H., Guggenheim, J. A., Holt, R. W., & Styles, I. B. (2012). Compressive sensing based reconstruction in bioluminescence tomography improves image resolution and robustness to noise. Biomedical Optics Express, 3(9), 2131-2141. Lien externe
Tichauer, K. M., Holt, R. W., Samkoe, K. S., El-Ghussein, F., Gunn, J. R., Jermyn, M., Dehghani, H., Leblond, F., & Pogue, B. W. (2012). Computed tomography-guided time-domain diffuse fluorescence tomography in small animals for localization of cancer biomarkers. Journal of Visualized Experiments (65), e4050. Disponible
Roberts, D. W., Valdés, P. A., Harris, B. T., Hartov, A., Fan, X., Ji, S., Leblond, F., Tosteson, T. D., Wilson, B. C., & Paulsen, K. D. (2012). Glioblastoma multiform treatment with clinical trials for surgical resection (aminolevulinic acid). Neurosurgery Clinics of North America, 23(3), 371-377. Lien externe
Valdes, P. A., Leblond, F., Jacobs, V. L., Paulsen, K. D., & Roberts, D. W. (2012). In vivo Fluorescence Detection in Surgery: A Review of Principles, Methods, and Clinical Applications. Current Medical Imaging Reviews, 8(3), 211-232. Lien externe
Bonfert-Taylor, P., Leblond, F., Holt, R. W., Tichauer, K. M., Pogue, B. W., & Taylor, E. C. (2012). Information loss and reconstruction in diffuse fluorescence tomography. Journal of the Optical Society of America A: Optics Image Science and Vision, 29(3), 321-330. Lien externe
Holt, R. W., Tichauer, K. M., Zhu, Q., Dehghani, H., Pogue, B. W., & Leblond, F. (2012). Multiple-gate time domain diffuse fluorescence tomography allows more sparse tissue sampling without compromising image quality. Optics Letters, 37(13), 2559-2561. Lien externe
Valdés, P. A., Leblond, F., Jacobs, V. L., Wilson, B. C., Paulsen, K. D., & Roberts, D. W. (2012). Quantitative, spectrally-resolved intraoperative fluorescence imaging. Scientific Reports, 2(1), 798. Disponible
Konecky, S. D., Owen, C. M., Rice, T., Valdes, P. A., Kolste, K., Wilson, B. C., Leblond, F., Roberts, D. W., Paulsen, K. D., & Tromberg, B. J. (2012). Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models. Journal of Biomedical Optics, 17. Lien externe
Valdés, P. A., Leblond, F., Kim, A., Wilson, B. C., Paulsen, K. D., & Roberts, D. W. (2012). A spectrally-constrained dual-band normalization technique for protoporphyrin IX quantification in fluorescence-guided surgery. Optics Letters, 37(11), 1817-1819. Lien externe
Orsini, P., Desroches, J., Daoust, F., Tavera, H., Dallaire, F., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (janvier 2023). Raman macroscopic imaging system for intraoperative brain cancer detection [Communication écrite]. SPIE BiOS 2023, San Francisco, California. Lien externe
Grajales, D., Le, W., Dallaire, F., Sheehy, G., David, S., Tran, T., Leblond, F., Menard, C., & Kadoury, S. (octobre 2023). Towards Real-Time Confirmation of Breast Cancer in the OR Using CNN-Based Raman Spectroscopy Classification [Communication écrite]. 2nd International Workshop on Cancer Prevention Through Early Detection (CaPTion 2023), Vancouver, BC, Canada. Lien externe
Maubois, B., Ksantini, N., & Leblond, F. (avril 2022). Development of a time-domain tissue imaging Raman spectroscopy system increasing inelastic scattering signal-tobackground ratio from early-photon time gating [Communication écrite]. Clinical and Translational Biophotonics 2022, Fort Lauderdale, FL, USA. Lien externe
St-Georges-Robillard, A., Masse, M., Patra, B., Orimoto, A. M., Strupler, M., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (octobre 2017). Chemosensitivity analysis of co-culture tumor spheroids on chip using hyperspectral fluorescence imaging [Communication écrite]. 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah, GA, USA. Non disponible
Laurence, A., Peng, K., Toffa, D., Robert, M., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (avril 2020). Localization of epileptic activity based on hemodynamics using an intraoperative hyperspectral imaging system [Communication écrite]. Clinical and Translational Biophotonics, Washington, D.C.. Lien externe
Laurence, A., Beaulieu, E., Nguyen, D. K., Bouthillier, A., Trudel, D., & Leblond, F. (juin 2019). Multimodal imaging platform for surgical guidance during epilepsy surgery [Communication écrite]. Diffuse Optical Spectroscopy and Imaging VII, Munich, Germany (4 pages). Lien externe
Shaikh, R., Guiot, M.-C., Petrecca, K., Tchaya, M., & Leblond, F. (avril 2019). Raman micro-spectroscopic study on brain tissue mapping [Communication écrite]. Bio-Optics: Design and Application (BODA 2019), Tucson, AZ. Lien externe
Picot, F., Goyette, A., Pichette, J., Tremblay, M.-A., Desroches, J., Obaid, S., Lessard, S., Soulez, G., & Leblond, F. (avril 2018). Diffusive reflectance spectroscopy to enhance safety during brain biopsy procedure [Communication écrite]. Biophotonics Congress (Optical Tomography and Spectroscopy 2018), Hollywood, Florida. Lien externe
St-Georges-Robillard, A., Cahuzac, M., Sauriol, A., Peant, B., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (novembre 2018). Quantifying ParPi-resistant subpopulations after treatment in co-culture spheroids using hyperspectral imaging [Communication écrite]. 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan. Non disponible
St-Georges-Robillard, A., Masse, M., Patra, B., Orimoto, A. M., Strupler, M., Mes-Masson, A. M., Leblond, F., & Gervais, T. (octobre 2017). Chemosensitivity analysis of co-culture spheroids on-chip using hyperspectral fluorescence imaging [Communication écrite]. 21st International Conference on Miniaturization in Chemistry and the Life Sciences (microTAS), Savannah, GA, ÉU. Non disponible
Desroches, J., Jermyn, M., Pinto, M., Picot, F., Tremblay, M.-A., Obaid, S., Guiot, M.-C., Petrecca, K., Wilson, B. C., & Leblond, F. (avril 2017). High wavenumber Raman spectroscopy to improve diagnostic yield of brain needle biopsies [Communication écrite]. Optics in the Life Sciences Congress, Optics and the Brain 2017. Lien externe
Aubertin, K., Trinh, V., Jermyn, M., Desroches, J., St-Pierre, C., Vladoiu, M.-C., Grosset, A.-A., Saad, F., Trudel, D., & Leblond, F. (février 2014). Raman Spectroscopy for Prostate Cancer Detection and Characterization [Communication écrite]. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA. Publié dans Biophysical Journal, 112(3). Lien externe
Aubertin, K., Quoc-Huy, T., Jermyn, M., St-Pierre, C., Vladoiu, M.-C., Grosset, A.-A., Saad, F., Trudel, D., & Leblond, F. (janvier 2017). Raman spectroscopy for prostate cancer detection and characterization (Conference Presentation) [Communication écrite]. Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive and Advanced Biomedical Devices, USA. Lien externe
Leblond, F. (janvier 2017). Taking label-free optical spectroscopy techniques into the operating theatre: biopsy needles and surgical guidance probes [Communication écrite]. Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis, USA (1 page). Lien externe
Pinto, M., Aubertin, K., Desroches, J., Jermyn, M., Trinh, V. Q., Vladoiu, M. C., Grosset, A. A., Lavallee, A. P., Benzyane, I., Benzyane, I., Benzyane, I., Faci, N., Richard, M. E., Duong, L., Haas, C., Badawy, Y., Saad, F., Zorn, K., Lesage, F., ... Trudel, D. (avril 2017). Towards live detection of cancerous tissue during radical prostatectomy using a raman spectroscopy probe [Communication écrite]. Bio-Optics: Design and Application (BODA 2017), San Diego, CA, United States. Lien externe
Picot, F., Pichette, J., Desroches, J., Goyette, A., Tremblay, M.-A., Ben-Mansour, Y., Leblond, F., Soulez, G., & Wilson, B. C. (mai 2016). Imaging system based on diffusive reflectance spectroscopy for blood vessels detection during brain biopsy procedure [Communication écrite]. Photonics North 2016, Québec City, Québec (1 page). Lien externe
Laurence, A., Pichette, J., Angulo-Rodríguez, L. M., Saint Pierre, C., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (février 2016). Intraoperative brain hemodynamic response assessment with real-time hyperspectral optical imaging [Communication écrite]. Clinical and Translational Neurophotonics, part of Photonics West 2016, San Francisco, California, United States. Lien externe
Madsen, S. J., Yang, V. X. D., Jansen, E. D., Luo, Q., Mohanty, S. K., Thakor, N. V., Angulo-Rodríguez, L. M., Laurence, A., Jermyn, M., Sheehy, G., Sibai, M., Petrecca, K., Roberts, D. W., Paulsen, K. D., Wilson, B. C., & Leblond, F. (février 2016). An intraoperative spectroscopic imaging system for quantification of protoporphyrin IX during glioma surgery [Communication écrite]. Clinical and Translational Neurophotonics, part of Photonics West 2016, San Francisco, California, United States. Lien externe
Vo-Dinh, T., Mahadevan-Jansen, A., Grundfest, W. S., Desroches, J., Pichette, J., Goyette, A., Tremblay, M.-A., Jermyn, M., Petrecca, K., & Leblond, F. (février 2016). Multimodal optical biopsy probe to improve the safety and diagnostic yield of brain needle biopsies [Communication écrite]. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, part of Photonics West 2016, San Francisco, California, USA. Lien externe
Jermyn, M., Desroches, J., Mercier, J., St-Arnaud, K., Guiot, M. C., Petrecca, K., & Leblond, F. (février 2016). Neural networks improve brain cancer detection with Raman spectroscopy in the presence of light artifacts [Communication écrite]. Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, USA (6 pages). Lien externe
Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Tearney, G. J., Gregory, K. W., Marcu, L., Skala, M. C., Campagnola, P. J., Mandelis, A., Morris, M. D., St-Georges-Robillard, A., Masse, M., Kendall-Dupont, J., Strupler, M., Patra, B., Jermyn, M., ... Gervais, T. (février 2016). Spectroscopic imaging system for high-throughput viability assessment of ovarian spheroids or microdissected tumor tissues (MDTs) in a microfluidic chip [Communication écrite]. Photonic Therapeutics and Diagnostics XII, San Francisco, California. Lien externe
Pichette, J., Goyette, A., Soulez, G., Wilson, B., & Leblond, F. (avril 2015). Development of a multispectral monte carlo simulation technique for blood vessels detection during brain needle biopsy procedures [Communication écrite]. Optics and the Brain (BRAIN 2015), Vancouver, Canada. Lien externe
Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Guiot, M. C., Petrecca, K., & Leblond, F. (février 2015). Intraoperative detection of glioma invasion beyond MRI enhancement with Raman spectroscopy in humans [Communication écrite]. SPIE Conference on Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, San Francisco, California (6 pages). Lien externe
Sibai, M., Veilleux, I., Elliott, J. T., Leblond, F., Roberts, D. W., & Wilson, B. C. (février 2015). Quantitative fluorescence imaging enabled by spatial frequency domain optical-property mapping in the sub-diffusive regime for surgical guidance [Communication écrite]. SPIE Conference on Molecular-Guided Surgery: Molecules, Devices, and Applications, San Francisco, California. Lien externe
Desroches, J., Goyette, A., Pichette, J., Jermyn, M., Mok, K., Mercier, J., Saint-Arnaud, K., Guiot, M.-C., Petrecca, K., Wilson, B. C., & Leblond, F. (avril 2015). Towards the combined use of Raman spectroscopy and interstitial optical tomography to improve the safety and diagnostic accuracy of brain needle biopsies [Communication écrite]. Optics and the Brain, part of Optics in the Life Sciences (BRAIN 2015), Vancouver, Canada. Lien externe
Beaulieu-Ouellet, E., Bélanger, S., Deterre, R., Gariépy, C., De Montigny, É., Leblond, F., Boudoux, C., & Lesage, F. (février 2014). Conference 8928A: Optical Techniques in Neurosurgery, Brain Imaging, and Neurobiology [Communication écrite]. 2014 Photonics West, San Francisco, California. Non disponible
Holt, R. W., Tichauer, K. M., El-Ghussein, F., Gunn, J. R., Leblond, F., & Pogue, B. W. (février 2013). Optimized methodology for low-contrast fluorescence recovery using a new approach for reference tracer normalization [Communication écrite]. Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United states. Lien externe
Tichauer, K. M., Holt, R. W., Leblond, F., & Pogue, B. W. (février 2013). An overview of time-domain diffuse fluorescence imaging: Instrumentation and applications [Communication écrite]. Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United states. Lien externe
Holt, R. W., Leblond, F., & Pogue, B. W. (février 2013). Toward ideal imaging geometry for recovery independence in fluorescence molecular tomography [Communication écrite]. Multimodal Biomedical Imaging VIII, San Francisco, CA, United states. Lien externe
Grosset, A.-A., St-Pierre, C., St-Arnaud, K., Aubertin, K., Jermyn, M., Leblond, F., & Trudel, D. (décembre 2017). Raman microscopy to assess biochemical recurrence risk after radical prostatectomy [Affiche]. AACR Special Conference on Prostate Cancer: Advances in Basic, Translational, and Clinical Research, Orlando, Florida, USA. Publié dans Cancer Research, 78(16). Lien externe
Aubertin, K., Birlea, M., Pinto, M., St-Arnaud, K., Trinh, V. Q., Grosset, A.-A., Leblond, F., & Trudel, D. (décembre 2017). Towards the use of Raman spectroscopy to guide prostate biopsy procedure [Affiche]. AACR Special Conference on Prostate Cancer: Advances in Basic, Translational, and Clinical Research, Orlando, Florida. Publié dans Cancer Research, 78(16). Lien externe
Grajales, D., Picot, F., Shams, R., Barkati, M., Delouya, G., Béliveau-Nadeau, D., Nicolas, B., Leblond, F., Menard, C., & Kadoury, S. (octobre 2021). In Vivo Confirmation of Prostate Tumor Burden During HDR Brachytherapy With a Combined Raman Spectroscopy and MRI Radiomics Approach [Résumé]. ASTRO 63rd Annual Meeting, Chicago, Illinois. Publié dans International Journal of Radiation Oncology Biology Physics, 111(3 (suppl.)). Lien externe
Grosset, A.-A., St-Pierre, C., Jermyn, M., Aubertin, K., Kougioumoutzakis, A., Pineau, M., St-Arnaud, K., Vladoiu, M. C., Leblond, F., & Trudel, D. (mars 2017). Improving Diagnostic Accuracy in the Pathology Workflow by Integration of Raman Microscopy [Résumé]. 106th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP 2017), San Antonio, TX. Publié dans Modern Pathology, 30(S2). Lien externe
Picot, F., Sheehy, G., Dallaire, F., Tremblay, J.-P., Daoust, F., Lemoine, É., Chaikho, L., Bégin, T., Petrecca, K., Kadoury, S., Leblond, F., Elson, D. S., Gioux, S., & Pogue, B. W. (avril 2020). Data compatibility across point probe Raman spectroscopy systems and its impact on statistical models portability (Conference Presentation) [Présentation]. Dans Clinical Biophotonics 2020. Lien externe
Leblond, F., Wax, A., & Backman, V. (février 2020). In situ molecular characterization and brain cancer detection using macroscopic spontaneous Raman spectroscopy imaging (Conference Presentation) [Présentation]. Dans Biomedical Applications of Light Scattering X, San Francisco, California, United States. Lien externe
Daoust, F., Orsini, P., Bismuth, J., de Denus-Baillargeon, M.-M., Veilleux, I., Wetter, A., McKoy, P., Dicaire, I., Massabki, M., Petrecca, K., Leblond, F., Petrich, W., & Huang, Z. (février 2020). Large field of view macroscopic Raman line-scanning imaging system for neuro-oncology applications (Conference Presentation) [Présentation]. Dans Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry, San Francisco, California, United States. Lien externe
Desroches, J., Jermyn, M., Marple, E., Urmey, K., Soulez, G., Guiot, M.-C., Wilson, B. C., Petrecca, K., Leblond, F., Vo-Dinh, T., Mahadevan-Jansen, A., & Grundfest, W. S. (janvier 2018). Integrated Raman biopsy probe for high yield targeted brain cancer biopsies (Conference Presentation) [Présentation]. Dans SPIE BiOS, San Francisco, California, United States. Lien externe
Leblond, F., Biggs, G., Pogue, B. W., & Gioux, S. (janvier 2018). Label-free optical spectroscopy techniques for targeted, real time and informed in situ cancer diagnosis (Conference Presentation) [Présentation]. Dans Molecular-Guided Surgery: Molecules, Devices, and Applications IV, San Francisco, California, United States. Lien externe
Valdes, P., Leblond, F., Paulsen, K. D., Campbell Wilson, B., Roberts, D. W., & Jermyn, M. (2023). Method and apparatus for quantitative and depth resolved hyperspectral fluorescence and reflectance imaging for surgical guidance. (Demande de brevet no US20230075997). Lien externe
Leblond, F., Petrecca, K., & Jermyn, M. (2017). System and method for assessing a cancer status of biological tissue. (Demande de brevet no US20170020460). Lien externe
Leblond, F., Wilson, B., Goyette, A., Pichette, J., Petrecca, K., Boudoux, C., Madore, W.-J., & Strupler, M. (2016). Biopsy device and method for obtaining a tomogram of a tissue volume using same. (Demande de brevet no US20160151055). Lien externe
Grosset, A.-A., Dallaire, F., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., Van Der Kwast, T., Orain, M., ... Trudel, D. (2020). Data from: Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation [Ensemble de données]. Lien externe