Documents dont l'auteur est "Leblond, Frédéric"

Frédéric LeblondDépartement de génie physique

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Nombre de documents: 126

Article de revue

Ember, K. J. I., Ksantini, N., Dallaire, F., Sheehy, G., Tran, T., Dehaes, M., Durand, M., Trudel, D., & Leblond, F. (2024). Liquid saliva-based Raman spectroscopy device with on-board machine learning detects COVID-19 infection in real-time. The Analyst, 149(22), 5535-5545. Disponible

Ember, K., Dallaire, F., Plante, A., Sheehy, G., Guiot, M.-C., Agarwal, R., Yadav, R., Douet, A., Selb, J., Tremblay, J. P., Dupuis, A., Marple, E., Urmey, K., Rizea, C., Harb, A., McCarthy, L., Schupper, A., Umphlett, M., Tsankova, N., ... Petrecca, K. (2024). In situ brain tumor detection using a Raman spectroscopy system — results of a multicenter study. Scientific Reports, 14, 14 (12 pages). Disponible

David, S., Tavera, H., Trang, T., Dallaire, F., Daoust, F., Tremblay, F., Richer, L., Meterissian, S., & Leblond, F. (2024). Macroscopic inelastic scattering imaging using a hyperspectral line-scanning system identifies invasive breast cancer in lumpectomy and mastectomy specimens. Journal of Biomedical Optics, 29(6), 065004 (16 pages). Disponible

Zamani, E., Ksantini, N., Sheehy, G., Ember, K. J. I., Baloukas, B., Zabeida, O., Trang, T., Mahfoud, M., Sapieha, J.-E., Martinu, L., & Leblond, F. (2024). Spectral effects and enhancement quantification in healthy human saliva with surface-enhanced Raman spectroscopy using silver nanopillar substrates. Lasers in Surgery and Medicine, 56(2), 206-217. Disponible

Grajales, D., Le, W. T., Tran, T., David, S., Dallaire, F., Ember, K., Leblond, F., Menard, C., & Kadoury, S. (2024). Robot-assisted biopsy sampling for online Raman spectroscopy cancer confirmation in the operating room. International Journal of Computer Assisted Radiology and Surgery, 9-9. Lien externe

David, S., Ksantini, N., Dallaire, F., Ember, K., Daoust, F., Sheehy, G., Hadjipanayis, C. G., Petrecca, K., Wilson, B. C., & Leblond, F. (2024). Toward noncontact macroscopic imaging of multiple cancers using multi-spectral inelastic scattering detection. Journal of Biophotonics, 2024000087 (7 pages). Lien externe

Daoust, F., Tavera, H., Dallaire, F., Orsini, P., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (2023). A clinical Raman spectroscopy imaging system and safety requirements for in situ intraoperative tissue characterization. Analyst, 148(9), 1991-2001. Lien externe

Bido, A. T., Ember, K. J. I., Trudel, D., Durand, M., Leblond, F., & Brolo, A. G. (2023). Detection of SARS-CoV-2 in saliva by a low-cost LSPR-based sensor. Analytical Methods, 32(32), 3955-3966. Lien externe

David, S., Tran, T., Dallaire, F., Sheehy, G., Azzi, F., Trudel, D., Tremblay, F., Omeroglu, A., Leblond, F., & Meterissian, S. (2023). In situ Raman spectroscopy and machine learning unveil biomolecular alterations in invasive breast cancer. Journal of Biomedical Optics, 28(3), 036009 (18 pages). Lien externe

Sheehy, G., Picot, F., Dallaire, F., Ember, K., Nguyen, T., Petrecca, K., Trudel, D., & Leblond, F. (2023). Open-sourced Raman spectroscopy data processing package implementing a baseline removal algorithm validated from multiple datasets acquired in human tissue and biofluids. Journal of Biomedical Optics, 28(2), 025002 (20 pages). Lien externe

Kosik, I., Dallaire, F., Pires, L., Tran, T., Leblond, F., & Wilson, B. (2023). Preclinical evaluation of Raman spectroscopy for pedicular screw insertion surgical guidance in a porcine spine model. Journal of Biomedical Optics, 28(5), 057003 (15 pages). Lien externe

Gagnon, J. R., Allen, C. H., Trudel, D., Leblond, F., Stys, P. K., Brideau, C., & Murugkar, S. (2023). Spectral focusing-based stimulated Raman scattering microscopy using compact glass blocks for adjustable dispersion. Biomedical Optics Express, 14(6), 2510-2522. Lien externe

Leblond, F., Dallaire, F., Tran, T., Yadav, R., Aubertin, K., Goudie, E., Romeo, P., Kent, C., Leduc, C., & Liberman, M. (2023). Subsecond lung cancer detection within a heterogeneous background of normal and benign tissue using single-point Raman spectroscopy. Journal of Biomedical Optics, 28(9), 090501 (8 pages). Lien externe

Blais-Ouellette, S., Rooney, D., Heller, D. A., Roxbury, D., Leblond, F., & Akbarzadeh, A. (2022). (Invited) Advances in Swir In Vivo Fluorescence Imaging Instrumentation. Meeting abstracts, MA2022-01(8), 676-676. Lien externe

Ember, K., Daoust, F., Mahfoud, M., Dallaire, F., Ahmad, E. Z., Tran, T., Plante, A., Diop, M.-K., Nguyen, T., St-Georges-Robillard, A., Ksantini, N., Lanthier, J., Filiatrault, A., Sheehy, G., Beaudoin, G., Quach, C., Trudel, D., & Leblond, F. (2022). Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning. Journal of Biomedical Optics, 27(2), 025002 (24 pages). Disponible

Picot, F., Shams, R., Dallaire, F., Sheehy, G., Trang, T., Grajales, D., Birlea, M., Trudel, D., Menard, C., Kadoury, S., & Leblond, F. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 1: Raman spectroscopy fiber-optics system and in situ tissue characterization. Journal of Biomedical Optics, 27(9), 095003 (14 pages). Lien externe

Lopera, D. O. G., Picot, F., Shams, R., Dallaire, F., Sheehy, G., Alley, S., Barkati, M., Delouya, G., Carrier, J.-F., Birlea, M., Trudel, D., Leblond, F., Menard, C., & Kadoury, S. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model combining spectral and MRI-radiomics features. Journal of Biomedical Optics, 27(9), 095004 (16 pages). Lien externe

Laurence, A., Toffa, D. H., Peng, K., Robert, M., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2022). Multispectral intraoperative imaging for the detection of the hemodynamic response to interictal epileptiform discharges. Biomedical Optics Express, 13(12), 6245-6257. Lien externe

David, S., Plante, A., Dallaire, F., Tremblay, J.-P., Sheehy, G., Macdonald, E., Forrest, L., Daneshmand, M., Trudel, D., Wilson, B. C., Hopkins, L., Murugkar, S., Vanderhyden, B., & Leblond, F. (2022). Multispectral label-free Raman spectroscopy can detect ovarian and endometrial cancer with high accuracy. Journal of Biophotonics, 15(2), 10 pages. Lien externe

Ciobanu, C., Ember, K. J. I., Nyíri, B. J., Rajan, S., Chauhan, V., Leblond, F., & Murugkar, S. (2022). Potential of Raman Spectroscopy for Blood-Based Biopsy. IEEE Instrumentation & Measurement Magazine, 25(1), 62-68. Lien externe

Ksantini, N., Veilleux, I., De Denus-Baillargeon, M.-M., Orsini, P., Dicaire, I., Lecourt, J.-B., Gognau, A., Hernandez, Y., Baylon, A., Massabki, M., Lesage, F., & Leblond, F. (2022). Time-gated interferometric detection increases Raman scattering to fluorescence signal ratio in biological samples. Journal of Biophotonics, 15(1), 6 pages. Lien externe

Plante, A., Dallaire, F., Grosset, A.-A., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., Van Der Kwast, T., ... Leblond, F. (2021). Dimensional reduction based on peak fitting of Raman micro spectroscopy data improves detection of prostate cancer in tissue specimens. Journal of Biomedical Optics, 26(11), 14 pages. Lien externe

Daoust, F., Nguyen, T., Orsini, P., Bismuth, J., De Denus-Baillargeon, M.-M., Veilleux, I., Wetter, A., McKoy, P., Dicaire, I., Massabki, M., Petrecca, K., & Leblond, F. (2021). Handheld macroscopic Raman spectroscopy imaging instrument for machine-learning-based molecular tissue margins characterization. Journal of Biomedical Optics, 26(2), 18 pages. Lien externe

Shabestri, B., Anastasio, M. A., Fei, B., & Leblond, F. (2021). Special Series Guest Editorial: Artificial Intelligence and Machine Learning in Biomedical Optics. Journal of Biomedical Optics, 26(5), 4 pages. Lien externe

Akbarzadeh, A., Edjlali, E., Sheehy, G., Selb, J., Agarwal, R., Weber, J., & Leblond, F. (2020). Experimental validation of a spectroscopic Monte Carlo light transport simulation technique and Raman scattering depth sensing analysis in biological tissue. Journal of Biomedical Optics, 25(10), 105002 (19 pages). Disponible

Picot, F., Daoust, F., Sheehy, G., Dallaire, F., Chaikho, L., Bégin, T., Kadoury, S., & Leblond, F. (2020). Data consistency and classification model transferability across biomedical Raman spectroscopy systems. Translational Biophotonics, 3(1), 1-11. Disponible

Dallaire, F., Picot, F., Tremblay, J.-P., Sheehy, G., Lemoine, É., Agarwal, R., Kadoury, S., Trudel, D., Lesage, F., Petrecca, K., & Leblond, F. (2020). Quantitative spectral quality assessment technique validated using intraoperative in vivo Raman spectroscopy measurements. Journal of Biomedical Optics, 25(4). Disponible

Beaulieu, E., Laurence, A., Birlea, M., Sheehy, G., Angulo-Rodriguez, L., Latour, M., Albadine, R., Saad, F., Trudel, D., & Leblond, F. (2020). Wide-field optical spectroscopy system integrating reflectance and spatial frequency domain imaging to measure attenuation-corrected intrinsic tissue fluorescence in radical prostatectomy specimens. Biomedical Optics Express, 11(4), 2052-2072. Disponible

Grosset, A.-A., Dallaire, F., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., van der Kwast, T., Orain, M., ... Trudel, D. (2020). Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation. Plos Medicine, 17(8), e1003281 (20 pages). Lien externe

Laurence, A., Bouthillier, A., Robert, M., Nguyen, D. K., & Leblond, F. (2020). Multispectral diffuse reflectance can discriminate blood vessels and bleeding during neurosurgery based on low-frequency hemodynamics. Journal of Biomedical Optics, 25(11), 10 pages. Lien externe

Shams, R., Picot, F., Grajales, D., Sheehy, G., Dallaire, F., Birlea, M., Saad, F., Trudel, D., Menard, C., Leblond, F., & Kadoury, S. (2020). Pre-clinical evaluation of an image-guided in-situ Raman spectroscopy navigation system for targeted prostate cancer interventions. International Journal of Computer Assisted Radiology and Surgery, 15(5), 867-876. Lien externe

Depaoli, D., Lemoine, É., Ember, K., Parent, M., Prud'Homme, M., Cantin, L., Petrecca, K., Leblond, F., & Cote, D. C. (2020). Rise of Raman spectroscopy in neurosurgery: A review. Journal of Biomedical Optics, 25(5), 36 pages. Lien externe

Picot, F., Goyette, A., Obaid, S., Desroches, J., Lessard, S., Tremblay, M.-A., Strupler, M., Wilson, B., Petrecca, K., Soulez, G., & Leblond, F. (2019). Interstitial imaging with multiple diffusive reflectance spectroscopy projections for in vivo blood vessels detection during brain needle biopsy procedures. Neurophotonics, 6(2), 025003 (8 pages). Disponible

St-Georges-Robillard, A., Cahuzac, M., Péant, B., Fleury, H., Lateef, M. A., Ricard, A., Sauriol, A., Leblond, F., Mes-Masson, A.-M., & Gervais, T. (2019). Long-term fluorescence hyperspectral imaging of on-chip treated co-culture tumour spheroids to follow clonal evolution. Integrative Biology, 11(4), 130-141. Disponible

Pinto, M., Zorn, K. C., Tremblay, J.-P., Desroches, J., Dallaire, F., Aubertin, K., Marple, E., Kent, C., Leblond, F., Trudel, D., & Lesage, F. (2019). Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures. Journal of Biomedical Optics, 24(2), 025001 (10 pages). Disponible

Desroches, J., Lemoine, É., Pinto, M., Marple, E., Urmey, K., Diaz, R., Guiot, M.-C., Wilson, B. C., Petrecca, K., & Leblond, F. (2019). Development and first in-human use of a Raman spectroscopy guidance system integrated with a brain biopsy needle. Journal of Biophotonics, 12(3), e201800396 (7 pages). Lien externe

Lemoine, É., Dallaire, F., Yadav, R., Agarwal, R., Kadoury, S., Trudel, D., Guiot, M.-C., Petrecca, K., & Leblond, F. (2019). Feature engineering applied to intraoperative in vivo Raman spectroscopy sheds light on molecular processes in brain cancer: a retrospective study of 65 patients. Analyst, 144(22), 6517-6532. Lien externe

Sibai, M., Wirth, D. J., Leblond, F., Roberts, D. W., Paulsen, K. D., & Wilson, B. C. (2019). Quantitative subsurface spatial frequency-domain fluorescence imaging for enhanced glioma resection. Journal of Biophotonics, 12(5), 6 pages. Lien externe

St-Georges-Robillard, A., Masse, M., Cahuzac, M., Strupler, M., Patra, B., Orimoto, A. M., Kendall-Dupont, J., Péant, B., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (2018). Fluorescence hyperspectral imaging for live monitoring of multiple spheroids in microfluidic chips. Analyst, 143(16), 3829-3840. Disponible

Desroches, J., Jermyn, M., Pinto, M., Picot, F., Tremblay, M.-A., Obaid, S., Marple, E., Urmey, K., Trudel, D., Soulez, G., Guiot, M.-C., Wilson, B. C., Petrecca, K., & Leblond, F. (2018). A new method using Raman spectroscopy for in vivo targeted brain cancer tissue biopsy. Scientific Reports, 8(1). Disponible

Wilson, B. C., Jermyn, M., & Leblond, F. (2018). Challenges and opportunities in clinical translation of biomedical optical spectroscopy and imaging. Journal of Biomedical Optics, 23(3), 13 pages. Lien externe

Aubertin, K., Desroches, J., Jermyn, M., Trinh, V. Q., Saad, F., Trudel, D., & Leblond, F. (2018). Combining high wavenumber and fingerprint raman spectroscopy for the detection of prostate cancer during radical prostatectomy. Biomedical Optics Express, 9(9), 4294-4305. Lien externe

St-Arnaud, K., Aubertin, K., Strupler, M., Madore, W.-J., Grosset, A.-A., Petrecca, K., Trudel, D., & Leblond, F. (2018). Development and characterization of a handheld hyperspectral Raman imaging probe system for molecular characterization of tissue on mesoscopic scales. Medical Physics, 45(1), 328-339. Lien externe

Aubertin, K., Quoc-Trinh, V., Jermyn, M., Baksic, P., Grosset, A.-A., Desroches, J., St-Arnaud, K., Birlea, M., Vladoiu, M. C., Latour, M., Albadine, R., Saad, F., Leblond, F., & Trudel, D. (2018). Mesoscopic characterization of prostate cancer using Raman spectroscopy : potential for diagnostics and therapeutics. BJU International, 122(2), 326-336. Lien externe

Roberts, D. W., Olson, J. D., Evans, L. T., Kolste, K. K., Kanick, S. C., Fan, X., Bravo, J. J., Wilson, B. C., Leblond, F., Marois, M., & Paulsen, K. D. (2018). Red-light excitation of protoporphyrin IX fluorescence for subsurface tumor detection. Journal of Neurosurgery, 128(6), 1690-1697. Lien externe

St-Pierre, C., Madore, W.-J., De Montigny, É., Trudel, D., Boudoux, C., Godbout, N., Mes-Masson, A.-M., Rahimi, K., & Leblond, F. (2017). Dimension reduction technique using a multilayered descriptor for high-precision classification of ovarian cancer tissue using optical coherence tomography: a feasibility study. Journal of Medical Imaging, 4(4), 13 pages. Lien externe

Wirth, D., Kolste, K., Kanick, S., Roberts, D. W., Leblond, F., & Paulsen, K. D. (2017). Fluorescence depth estimation from wide-field optical imaging data for guiding brain tumor resection: A multi-inclusion phantom study. Biomedical Optics Express, 8(8), 3656-3670. Lien externe

Jermyn, M., Mercier, J., Aubertin, K., Desroches, J., Urmey, K., Karamchandiani, J., Marple, E., Guiot, M.-C., Leblond, F., & Petrecca, K. (2017). Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy. Cancer Research, 77(14), 3942-3950. Lien externe

Gough, K. M., & Leblond, F. (2017). Optical diagnosis: Highlighting the clinical applications of vibrational spectroscopy. Analyst, 142(8), 1177-1178. Lien externe

Sibai, M., Fisher, C., Veilleux, I., Elliott, J. T., Leblond, F., Roberts, D. W., & Wilson, B. C. (2017). Preclinical evaluation of spatial frequency domain-enabled wide-field quantitative imaging for enhanced glioma resection. Journal of Biomedical Optics, 22(7), 10 pages. Lien externe

Desroches, J., Laurence, A., Jermyn, M., Pinto, M., Tremblay, M.-A., Petrecca, K., & Leblond, F. (2017). Raman spectroscopy in microsurgery: impact of operating microscope illumination sources on data quality and tissue classification. Analyst, 142(8), 1185-1191. Lien externe

Pichette, J., Laurence, A., Angulo, L., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2016). Intraoperative video-rate hemodynamic response assessment in human cortex using snapshot hyperspectral optical imaging. Neurophotonics, 3(4). Lien externe

Astolfi, M., St-Georges-Robillard, A., Leblond, F., Mes-Masson, A.-M., & Gervais, T. (2016). Microfluidics and spectroscopic imaging for personalized medicine in ovarian cancer. SPIE Newsroom. Lien externe

Jermyn, M., Desroches, J., Mercier, J., Tremblay, M.-A., St-Arnaud, K., Guiot, M.-C., Petrecca, K., & Leblond, F. (2016). Neural networks improve brain cancer detection with Raman spectroscopy in the presence of operating room light artifacts. Journal of Biomedical Optics, 21(9). Lien externe

Jermyn, M., Desroches, J., Mercier, J., St-Arnaud, K., Guiot, M.-C., Leblond, F., & Petrecca, K. (2016). Raman spectroscopy detects distant invasive brain cancer cells centimeters beyond MRI capability in humans. Biomedical Optics Express, 7(12), 5129-5137. Lien externe

Jermyn, M., Desroches, J., Aubertin, K., St-Arnaud, K., Madore, W.-J., De Montigny, E., Guiot, M.-C., Trudel, D., Wilson, B. C., Petrecca, K., & Leblond, F. (2016). A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology. Physics in Medicine and Biology, 61(23), R370-R400. Lien externe

St-Arnaud, K., Aubertin, K., Strupler, M., Jermyn, M., Petrecca, K., Trudel, D., & Leblond, F. (2016). Wide-field spontaneous Raman spectroscopy imaging system for biological tissue interrogation. Optics Letters, 41(20), 4692-4695. Lien externe

Desroches, J., Jermyn, M., Mok, K., Lemieux-Leduc, C., Mercier, J., St-Arnaud, K., Urmey, K., Guiot, M.-C., Marple, E., Petrecca, K., & Leblond, F. (2015). Characterization of a Raman spectroscopy probe system for intraoperative brain tissue classification. Biomedical Optics Express, 6(7), 2380-2397. Lien externe

Jermyn, M., Gosselin, Y., Valdes, P. A., Sibai, M., Kolste, K., Mercier, J., Angulo, L., Roberts, D. W., Paulsen, K. D., Petrecca, K., Daigle, O., Wilson, B. C., & Leblond, F. (2015). Improved sensitivity to fluorescence for cancer detection in wide-field image-guided neurosurgery. Biomedical Optics Express, 6(12), 5063-5074. Lien externe

Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Bernstein, L., Guiot, M. C., Petrecca, K., & Leblond, F. (2015). Intraoperative brain cancer detection with Raman spectroscopy in humans. Science Translational Medicine, 7(274), 9-9. Lien externe

Leblond, F., Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Guiot, M.-C., & Petrecca, K. (2015). Intraoperative detection of cancerous brain tissue using Raman spectroscopy. SPIE Newsroom. Lien externe

Kolste, K. K., Kanick, S. C., Valdés, P. A., Jermyn, M., Wilson, B. C., Roberts, D. W., Paulsen, K. D., & Leblond, F. (2015). Macroscopic optical imaging technique for wide-field estimation of fluorescence depth in optically turbid media for application in brain tumor surgical guidance. Journal of Biomedical Optics, 20(2), 026002 (8 pages). Lien externe

Jermyn, M., Kolste, K., Pichette, J., Sheehy, G., Angulo-Rodriguez, L., Paulsen, K. D., Roberts, D. W., Wilson, B. C., Petrecca, K., & Leblond, F. (2015). Macroscopic-imaging technique for subsurface quantification of near-infrared markers during surgery. Journal of Biomedical Optics, 20(3). Lien externe

Valdés, P. A., Jacobs, V., Harris, B. T., Wilson, B. C., Leblond, F., Paulsen, K. D., & Roberts, D. W. (2015). Quantitative fluorescence using 5-aminolevulinic acid-induced protoporphyrin IX biomarker as a surgical adjunct in low-grade glioma surgery. Journal of Neurosurgery, 123(3), 771-780. Lien externe

Sibai, M., Veilleux, I., Elliott, J. T., Leblond, F., & Wilson, B. C. (2015). Quantitative spatial frequency fluorescence imaging in the sub-diffusive domain for image-guided glioma resection. Biomedical Optics Express, 6(12), 4923-4933. Lien externe

Pichette, J., Goyette, A., Picot, F., Tremblay, M.-A., Soulez, G., Wilson, B. C., & Leblond, F. (2015). Sensitivity analysis aimed at blood vessels detection using interstitial optical tomography during brain needle biopsy procedures. Biomedical Optics Express, 6(11), 4238-4254. Lien externe

Goyette, A., Pichette, J., Tremblay, M.-A., Laurence, A., Jermyn, M., Mok, K., Paulsen, K. D., Roberts, D. W., Petrecca, K., Wilson, B. C., & Leblond, F. (2015). Sub-diffuse interstitial optical tomography to improve the safety of brain needle biopsies: a proof-of-concept study. Optics Letters, 40(2), 170-173. Lien externe

Valdes, P. A., Bekelis, K., Harris, B. T., Wilson, B. C., Leblond, F., Kim, A., Simmons, N. E., Erkmen, K., Paulsen, K. D., & Roberts, D. W. (2014). 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence in Meningioma: Qualitative and Quantitative Measurements In Vivo. Neurosurgery, 10(1), 74-82. Lien externe

Thouin, F., Leblond, F., Martel, R., Verhaegen, M., & Daigle, O. (2014). Ultra Fast Raman Hyperspectral Imaging using Bragg Tunable Filters and a High Performance Emccd Camera. Biophysical Journal, 106(2), 613A-613A. Lien externe

Tichauer, K. M., Holt, R. W., El-Ghussein, F., Davis, S. C., Samkoe, K. S., Gunn, J. R., Leblond, F., & Pogue, B. W. (2013). Dual-tracer background subtraction approach for fluorescent molecular tomography. Journal of Biomedical Optics, 18(1), 16003. Disponible

Holt, R. W., Leblond, F., & Pogue, B. W. (2013). Methodology to Optimize Detector Geometry in Fluorescence Tomography of Tissue Using the Minimized Curvature of the Summed Diffuse Sensitivity Projections. Journal of the Optical Society of America A: Optics Image Science and Vision, 30(8), 1613-1619. Lien externe

Roberts, D. W., Valdés, P. A., Harris, B. T., Hartov, A., Fan, X., Ji, S., Pogue, B. W., Leblond, F., Tosteson, T. D., Wilson, B. C., & Paulsen, K. D. (2012). Adjuncts for maximizing resection: 5-aminolevuinic acid. Clinical Neurosurgery, 59(Supplement), 75-78. Lien externe

Basevi, H. R. A., Tichauer, K. M., Leblond, F., Pogue, B. W., Dehghani, H., Guggenheim, J. A., Holt, R. W., & Styles, I. B. (2012). Compressive sensing based reconstruction in bioluminescence tomography improves image resolution and robustness to noise. Biomedical Optics Express, 3(9), 2131-2141. Lien externe

Tichauer, K. M., Holt, R. W., Samkoe, K. S., El-Ghussein, F., Gunn, J. R., Jermyn, M., Dehghani, H., Leblond, F., & Pogue, B. W. (2012). Computed tomography-guided time-domain diffuse fluorescence tomography in small animals for localization of cancer biomarkers. Journal of Visualized Experiments (65), e4050. Disponible

Roberts, D. W., Valdés, P. A., Harris, B. T., Hartov, A., Fan, X., Ji, S., Leblond, F., Tosteson, T. D., Wilson, B. C., & Paulsen, K. D. (2012). Glioblastoma multiform treatment with clinical trials for surgical resection (aminolevulinic acid). Neurosurgery Clinics of North America, 23(3), 371-377. Lien externe

Valdes, P. A., Leblond, F., Jacobs, V. L., Paulsen, K. D., & Roberts, D. W. (2012). In vivo Fluorescence Detection in Surgery: A Review of Principles, Methods, and Clinical Applications. Current Medical Imaging Reviews, 8(3), 211-232. Lien externe

Bonfert-Taylor, P., Leblond, F., Holt, R. W., Tichauer, K. M., Pogue, B. W., & Taylor, E. C. (2012). Information loss and reconstruction in diffuse fluorescence tomography. Journal of the Optical Society of America A: Optics Image Science and Vision, 29(3), 321-330. Lien externe

Holt, R. W., Tichauer, K. M., Zhu, Q., Dehghani, H., Pogue, B. W., & Leblond, F. (2012). Multiple-gate time domain diffuse fluorescence tomography allows more sparse tissue sampling without compromising image quality. Optics Letters, 37(13), 2559-2561. Lien externe

Valdés, P. A., Leblond, F., Jacobs, V. L., Wilson, B. C., Paulsen, K. D., & Roberts, D. W. (2012). Quantitative, spectrally-resolved intraoperative fluorescence imaging. Scientific Reports, 2(1), 798. Disponible

Konecky, S. D., Owen, C. M., Rice, T., Valdes, P. A., Kolste, K., Wilson, B. C., Leblond, F., Roberts, D. W., Paulsen, K. D., & Tromberg, B. J. (2012). Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models. Journal of Biomedical Optics, 17. Lien externe

Valdés, P. A., Leblond, F., Kim, A., Wilson, B. C., Paulsen, K. D., & Roberts, D. W. (2012). A spectrally-constrained dual-band normalization technique for protoporphyrin IX quantification in fluorescence-guided surgery. Optics Letters, 37(11), 1817-1819. Lien externe

Communication écrite

Lee, S. S., Beaudoin, G., Yeoh, J. H., Leblond, F., Trifiro, M., & Paliouras, M. (avril 2024). Abstract 4168: Pre-clinical demonstration of Raman spectroscopy-assisted photothermal therapy for prostate cancer [Communication écrite]. AACR Annual Meeting 2024, San Diego, California. Publié dans Cancer Research, 84(6_Suppl.). Lien externe

Orsini, P., Desroches, J., Daoust, F., Tavera, H., Dallaire, F., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (janvier 2023). Raman macroscopic imaging system for intraoperative brain cancer detection [Communication écrite]. SPIE BiOS 2023, San Francisco, California. Lien externe

Grajales, D., Le, W., Dallaire, F., Sheehy, G., David, S., Tran, T., Leblond, F., Menard, C., & Kadoury, S. (octobre 2023). Towards Real-Time Confirmation of Breast Cancer in the OR Using CNN-Based Raman Spectroscopy Classification [Communication écrite]. 2nd International Workshop on Cancer Prevention Through Early Detection (CaPTion 2023), Vancouver, BC, Canada. Lien externe

Maubois, B., Ksantini, N., & Leblond, F. (avril 2022). Development of a time-domain tissue imaging Raman spectroscopy system increasing inelastic scattering signal-to-background ratio from early-photon time gating [Communication écrite]. Clinical and Translational Biophotonics 2022, Fort Lauderdale, FL, USA. Lien externe

St-Georges-Robillard, A., Masse, M., Patra, B., Orimoto, A. M., Strupler, M., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (octobre 2017). Chemosensitivity analysis of co-culture tumor spheroids on chip using hyperspectral fluorescence imaging [Communication écrite]. 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah, GA, USA. Non disponible

Laurence, A., Peng, K., Toffa, D., Robert, M., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (avril 2020). Localization of epileptic activity based on hemodynamics using an intraoperative hyperspectral imaging system [Communication écrite]. Clinical and Translational Biophotonics, Washington, D.C.. Lien externe

Laurence, A., Beaulieu, E., Nguyen, D. K., Bouthillier, A., Trudel, D., & Leblond, F. (juin 2019). Multimodal imaging platform for surgical guidance during epilepsy surgery [Communication écrite]. Diffuse Optical Spectroscopy and Imaging VII, Munich, Germany (4 pages). Lien externe

Shaikh, R., Guiot, M.-C., Petrecca, K., Tchaya, M., & Leblond, F. (avril 2019). Raman micro-spectroscopic study on brain tissue mapping [Communication écrite]. Bio-Optics: Design and Application (BODA 2019), Tucson, AZ. Lien externe

Picot, F., Goyette, A., Pichette, J., Tremblay, M.-A., Desroches, J., Obaid, S., Lessard, S., Soulez, G., & Leblond, F. (avril 2018). Diffusive reflectance spectroscopy to enhance safety during brain biopsy procedure [Communication écrite]. Biophotonics Congress (Optical Tomography and Spectroscopy 2018), Hollywood, Florida. Lien externe

St-Georges-Robillard, A., Cahuzac, M., Sauriol, A., Peant, B., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (novembre 2018). Quantifying ParPi-resistant subpopulations after treatment in co-culture spheroids using hyperspectral imaging [Communication écrite]. 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan. Non disponible

St-Georges-Robillard, A., Masse, M., Patra, B., Orimoto, A. M., Strupler, M., Mes-Masson, A. M., Leblond, F., & Gervais, T. (octobre 2017). Chemosensitivity analysis of co-culture spheroids on-chip using hyperspectral fluorescence imaging [Communication écrite]. 21st International Conference on Miniaturization in Chemistry and the Life Sciences (microTAS), Savannah, GA, ÉU. Non disponible

Desroches, J., Jermyn, M., Pinto, M., Picot, F., Tremblay, M.-A., Obaid, S., Guiot, M.-C., Petrecca, K., Wilson, B. C., & Leblond, F. (avril 2017). High wavenumber Raman spectroscopy to improve diagnostic yield of brain needle biopsies [Communication écrite]. Optics and the Brain 2017, San Diego, California, United States. Lien externe

Aubertin, K., Trinh, V., Jermyn, M., Desroches, J., St-Pierre, C., Vladoiu, M.-C., Grosset, A.-A., Saad, F., Trudel, D., & Leblond, F. (février 2014). Raman Spectroscopy for Prostate Cancer Detection and Characterization [Communication écrite]. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA. Publié dans Biophysical Journal, 112(3). Lien externe

Aubertin, K., Quoc-Huy, T., Jermyn, M., St-Pierre, C., Vladoiu, M.-C., Grosset, A.-A., Saad, F., Trudel, D., & Leblond, F. (janvier 2017). Raman spectroscopy for prostate cancer detection and characterization (Conference Presentation) [Communication écrite]. Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive and Advanced Biomedical Devices, USA. Lien externe

Leblond, F. (janvier 2017). Taking label-free optical spectroscopy techniques into the operating theatre: biopsy needles and surgical guidance probes [Communication écrite]. Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis, USA (1 page). Lien externe

Pinto, M., Aubertin, K., Desroches, J., Jermyn, M., Trinh, V. Q., Vladoiu, M. C., Grosset, A. A., Lavallee, A. P., Benzyane, I., Benzyane, I., Benzyane, I., Faci, N., Richard, M. E., Duong, L., Haas, C., Badawy, Y., Saad, F., Zorn, K., Lesage, F., ... Trudel, D. (avril 2017). Towards live detection of cancerous tissue during radical prostatectomy using a raman spectroscopy probe [Communication écrite]. Bio-Optics: Design and Application (BODA 2017), San Diego, CA, United States. Lien externe

Picot, F., Pichette, J., Desroches, J., Goyette, A., Tremblay, M.-A., Ben-Mansour, Y., Leblond, F., Soulez, G., & Wilson, B. C. (mai 2016). Imaging system based on diffusive reflectance spectroscopy for blood vessels detection during brain biopsy procedure [Communication écrite]. Photonics North 2016, Québec City, Québec (1 page). Lien externe

Laurence, A., Pichette, J., Angulo-Rodríguez, L. M., Saint Pierre, C., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (février 2016). Intraoperative brain hemodynamic response assessment with real-time hyperspectral optical imaging [Communication écrite]. Clinical and Translational Neurophotonics, part of Photonics West 2016, San Francisco, California, United States. Lien externe

Madsen, S. J., Yang, V. X. D., Jansen, E. D., Luo, Q., Mohanty, S. K., Thakor, N. V., Angulo-Rodríguez, L. M., Laurence, A., Jermyn, M., Sheehy, G., Sibai, M., Petrecca, K., Roberts, D. W., Paulsen, K. D., Wilson, B. C., & Leblond, F. (février 2016). An intraoperative spectroscopic imaging system for quantification of protoporphyrin IX during glioma surgery [Communication écrite]. Clinical and Translational Neurophotonics, part of Photonics West 2016, San Francisco, California, United States. Lien externe

Vo-Dinh, T., Mahadevan-Jansen, A., Grundfest, W. S., Desroches, J., Pichette, J., Goyette, A., Tremblay, M.-A., Jermyn, M., Petrecca, K., & Leblond, F. (février 2016). Multimodal optical biopsy probe to improve the safety and diagnostic yield of brain needle biopsies [Communication écrite]. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, part of Photonics West 2016, San Francisco, California, USA. Lien externe

Jermyn, M., Desroches, J., Mercier, J., St-Arnaud, K., Guiot, M. C., Petrecca, K., & Leblond, F. (février 2016). Neural networks improve brain cancer detection with Raman spectroscopy in the presence of light artifacts [Communication écrite]. Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, USA (6 pages). Lien externe

Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Tearney, G. J., Gregory, K. W., Marcu, L., Skala, M. C., Campagnola, P. J., Mandelis, A., Morris, M. D., St-Georges-Robillard, A., Masse, M., Kendall-Dupont, J., Strupler, M., Patra, B., Jermyn, M., ... Gervais, T. (février 2016). Spectroscopic imaging system for high-throughput viability assessment of ovarian spheroids or microdissected tumor tissues (MDTs) in a microfluidic chip [Communication écrite]. Photonic Therapeutics and Diagnostics XII, San Francisco, California. Lien externe

Pichette, J., Goyette, A., Soulez, G., Wilson, B., & Leblond, F. (avril 2015). Development of a multispectral monte carlo simulation technique for blood vessels detection during brain needle biopsy procedures [Communication écrite]. Optics and the Brain (BRAIN 2015), Vancouver, Canada. Lien externe

Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Guiot, M. C., Petrecca, K., & Leblond, F. (février 2015). Intraoperative detection of glioma invasion beyond MRI enhancement with Raman spectroscopy in humans [Communication écrite]. SPIE Conference on Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, San Francisco, California (6 pages). Lien externe

Sibai, M., Veilleux, I., Elliott, J. T., Leblond, F., Roberts, D. W., & Wilson, B. C. (février 2015). Quantitative fluorescence imaging enabled by spatial frequency domain optical-property mapping in the sub-diffusive regime for surgical guidance [Communication écrite]. SPIE Conference on Molecular-Guided Surgery: Molecules, Devices, and Applications, San Francisco, California. Lien externe

Desroches, J., Goyette, A., Pichette, J., Jermyn, M., Mok, K., Mercier, J., Saint-Arnaud, K., Guiot, M.-C., Petrecca, K., Wilson, B. C., & Leblond, F. (avril 2015). Towards the combined use of Raman spectroscopy and interstitial optical tomography to improve the safety and diagnostic accuracy of brain needle biopsies [Communication écrite]. Optics and the Brain, part of Optics in the Life Sciences (BRAIN 2015), Vancouver, Canada. Lien externe

Beaulieu-Ouellet, E., Bélanger, S., Deterre, R., Gariépy, C., De Montigny, É., Leblond, F., Boudoux, C., & Lesage, F. (février 2014). Conference 8928A: Optical Techniques in Neurosurgery, Brain Imaging, and Neurobiology [Communication écrite]. 2014 Photonics West, San Francisco, California. Non disponible

Holt, R. W., Tichauer, K. M., El-Ghussein, F., Gunn, J. R., Leblond, F., & Pogue, B. W. (février 2013). Optimized methodology for low-contrast fluorescence recovery using a new approach for reference tracer normalization [Communication écrite]. Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United states. Lien externe

Tichauer, K. M., Holt, R. W., Leblond, F., & Pogue, B. W. (février 2013). An overview of time-domain diffuse fluorescence imaging: Instrumentation and applications [Communication écrite]. Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United states. Lien externe

Holt, R. W., Leblond, F., & Pogue, B. W. (février 2013). Toward ideal imaging geometry for recovery independence in fluorescence molecular tomography [Communication écrite]. Multimodal Biomedical Imaging VIII, San Francisco, CA, United states. Lien externe

Affiche

Grosset, A.-A., St-Pierre, C., St-Arnaud, K., Aubertin, K., Jermyn, M., Leblond, F., & Trudel, D. (décembre 2017). Raman microscopy to assess biochemical recurrence risk after radical prostatectomy [Affiche]. AACR Special Conference on Prostate Cancer: Advances in Basic, Translational, and Clinical Research, Orlando, Florida, USA. Publié dans Cancer Research, 78(16). Lien externe

Aubertin, K., Birlea, M., Pinto, M., St-Arnaud, K., Trinh, V. Q., Grosset, A.-A., Leblond, F., & Trudel, D. (décembre 2017). Towards the use of Raman spectroscopy to guide prostate biopsy procedure [Affiche]. AACR Special Conference on Prostate Cancer: Advances in Basic, Translational, and Clinical Research, Orlando, Florida. Publié dans Cancer Research, 78(16). Lien externe

Résumé

Grajales, D., Picot, F., Shams, R., Barkati, M., Delouya, G., Béliveau-Nadeau, D., Nicolas, B., Leblond, F., Menard, C., & Kadoury, S. (octobre 2021). In Vivo Confirmation of Prostate Tumor Burden During HDR Brachytherapy With a Combined Raman Spectroscopy and MRI Radiomics Approach [Résumé]. ASTRO 63rd Annual Meeting, Chicago, Illinois. Publié dans International Journal of Radiation Oncology Biology Physics, 111(3 (suppl.)). Lien externe

Grosset, A.-A., St-Pierre, C., Jermyn, M., Aubertin, K., Kougioumoutzakis, A., Pineau, M., St-Arnaud, K., Vladoiu, M. C., Leblond, F., & Trudel, D. (mars 2017). Improving Diagnostic Accuracy in the Pathology Workflow by Integration of Raman Microscopy [Résumé]. 106th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP 2017), San Antonio, TX. Publié dans Modern Pathology, 30(S2). Lien externe

Présentation

Leblond, F., David, S., Pahlavani, S., Ksantini, N., Dallaire, F., Sheehy, G., Hadjapanayis, C., Petrecca, K., & Wilson, B. C. (janvier 2024). Towards non-contact and real-time large field-of-view single-band Raman spectroscopy imaging in brain cancer surgery [Présentation]. Dans SPIE Photonics West 2024, San Francisco, Ca, United States. Lien externe

Ember, K., Ksantini, N., Dallaire, F., Sheehy, G., Noé, A., Tran, T., Durand, M., Trudel, D., & Leblond, F. (janvier 2024). Rapid detection of COVID-19 in liquid saliva using reagent-free Raman spectroscopy [Présentation]. Dans SPIE Photonics West 2024, San Francisco, California, United States. Lien externe

Picot, F., Sheehy, G., Dallaire, F., Tremblay, J.-P., Daoust, F., Lemoine, É., Chaikho, L., Bégin, T., Petrecca, K., Kadoury, S., Leblond, F., Elson, D. S., Gioux, S., & Pogue, B. W. (avril 2020). Data compatibility across point probe Raman spectroscopy systems and its impact on statistical models portability (Conference Presentation) [Présentation]. Dans Clinical Biophotonics 2020. Lien externe

Leblond, F., Wax, A., & Backman, V. (février 2020). In situ molecular characterization and brain cancer detection using macroscopic spontaneous Raman spectroscopy imaging (Conference Presentation) [Présentation]. Dans Biomedical Applications of Light Scattering X, San Francisco, California, United States. Lien externe

Daoust, F., Orsini, P., Bismuth, J., De Denus-Baillargeon, M.-M., Veilleux, I., Wetter, A., McKoy, P., Dicaire, I., Massabki, M., Petrecca, K., Leblond, F., Petrich, W., & Huang, Z. (février 2020). Large field of view macroscopic Raman line-scanning imaging system for neuro-oncology applications (Conference Presentation) [Présentation]. Dans Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry, San Francisco, California, United States. Lien externe

Desroches, J., Jermyn, M., Marple, E., Urmey, K., Soulez, G., Guiot, M.-C., Wilson, B. C., Petrecca, K., Leblond, F., Vo-Dinh, T., Mahadevan-Jansen, A., & Grundfest, W. S. (janvier 2018). Integrated Raman biopsy probe for high yield targeted brain cancer biopsies (Conference Presentation) [Présentation]. Dans SPIE BiOS, San Francisco, California, United States. Lien externe

Leblond, F., Biggs, G., Pogue, B. W., & Gioux, S. (janvier 2018). Label-free optical spectroscopy techniques for targeted, real time and informed in situ cancer diagnosis (Conference Presentation) [Présentation]. Dans Molecular-Guided Surgery: Molecules, Devices, and Applications IV, San Francisco, California, United States. Lien externe

Demande de brevet

Valdes, P., Leblond, F., Paulsen, K. D., Campbell Wilson, B., Roberts, D. W., & Jermyn, M. (2023). Method and apparatus for quantitative and depth resolved hyperspectral fluorescence and reflectance imaging for surgical guidance. (Demande de brevet no US20230075997). Lien externe

Leblond, F., Petrecca, K., & Jermyn, M. (2017). System and method for assessing a cancer status of biological tissue. (Demande de brevet no US20170020460). Lien externe

Leblond, F., Wilson, B., Goyette, A., Pichette, J., Petrecca, K., Boudoux, C., Madore, W.-J., & Strupler, M. (2016). Biopsy device and method for obtaining a tomogram of a tissue volume using same. (Demande de brevet no US20160151055). Lien externe

Ensemble de données

Grosset, A.-A., Dallaire, F., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., Van Der Kwast, T., Orain, M., ... Trudel, D. (2020). Data from: Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation [Ensemble de données]. Lien externe

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