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Items where Author is "Lavertu, Marc"

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Number of items: 75.

2024

Alameh, M.‐G., Naeini, A. T., Dwivedi, G., Lesage, F., Buschmann, M. D., & Lavertu, M. (2024). Chitosan siRNA nanoparticles produce significant non-toxic functional gene silencing in Kidney Cortices. Polymers, 16(17), 2547 (22 pages). Available

BenDavid, E., Ramezanian, S., Lu, Y., Rousseau, J., Schroeder, A., Lavertu, M., & Tremblay, J. P. (2024). Emerging perspectives on prime editor delivery to the brain. Pharmaceuticals, 17(6), 763 (42 pages). Available

2023

Milano, F., Chevrier, A., De Crescenzo, G., & Lavertu, M. (2023). Injectable Lyophilized Chitosan-Thrombin-Platelet-Rich Plasma (CS-FIIa-PRP) Implant to Promote Tissue Regeneration: In Vitro and Ex Vivo Solidification Properties. Polymers, 15(13), 2919 (15 pages). Available

Han, X., Alameh, M.-G., Butowska, K., Knox, J. J., Lundgreen, K., Ghattas, M., Gong, N., Xue, L., Xu, Y., Lavertu, M., Bates, P., Xu, J., Nie, G., Zhong, Y., Weissman, D., & Mitchell, M. J. (2023). Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines. Nature Nanotechnology, 18(9), 1105-1114. External link

Liu, X., Beaudoin, G., Zhang, H., Esquivel Guzmán, J. A., Le Roux, É., Pellerin, C., Rivera, E., Lavertu, M., & Zhu, X. X. (2023). Chlorophyllin-Containing Copolymers and Their Responsive Properties. ACS Applied Bio Materials, 7 pages. External link

2022

Chevrier, A., Hurtig, M. B., & Lavertu, M. (2022). Chitosan-platelet-rich plasma implants improve rotator cuff repair in a large animal model: Pilot study. Journal of Biomaterials Applications, 37(2), 183-194. External link

Naeini, A. T., Alameh, M.-G., Soliman, O. Y., & Lavertu, M. (2022). Purification and Surface Modification of Chitosan-based Polyplexes Using Tangential Flow Filtration and Coating by Hyaluronic Acid. Journal of Pharmaceutical Sciences, 111(10), 2857-2866. External link

Esquivel Guzmán, J. A., Zhang, H., Mohanty, C., Liu, X., Rivera, E., Illescas, J., Lavertu, M., & Zhu, X. X. (2022). Thermoresponsive copolymers based on synthetic porphyrin derivatives. MRS Advances, 7(34), 1126-1132. External link

2021

Chevrier, A., Hurtig, M. B., & Lavertu, M. (2021). Chitosan-Platelet-Rich Plasma Implants Improve Rotator Cuff Repair in a Large Animal Model: Pivotal Study. Pharmaceutics, 13(11), 1955 (16 pages). External link

Jeandupeux, E., Alameh, M.-G., Ghattas, M., De Crescenzo, G., & Lavertu, M. (2021). Poly(2-Propylacrylic Acid) Increases In Vitro Bioactivity of Chitosan/mRNA Nanoparticles. Journal of Pharmaceutical Sciences, 110(10), 3439-3449. External link

Esquivel Guzmán, J. A., Zhang, H., Rivera, E., Lavertu, M., & Zhu, X.-X. (2021). Porphyrin-Based Polyesters Synthesized by Enzymatic Catalysis. ACS Applied Polymer Materials, 3(7), 3659-3665. External link

Milano, F., Chevrier, A., De Crescenzo, G., & Lavertu, M. (2021). Robust Segmentation-Free Algorithm for Homogeneity Quantification in Images. IEEE Transactions on Image Processing, 30, 5533-5544. External link

Ghattas, M., Dwivedi, G., Lavertu, M., & Alameh, M.-G. (2021). Vaccine Technologies and Platforms for Infectious Diseases: Current Progress, Challenges, and Opportunities. Vaccines, 9(12), 1490 (31 pages). External link

2020

Soliman, O. Y., Alameh, M. G., De Crescenzo, G., Buschmann, M. D., & Lavertu, M. (2020). Efficiency of Chitosan/Hyaluronan-Based mRNA Delivery Systems In Vitro: Influence of Composition and Structure. Journal of Pharmaceutical Sciences, 109(4), 1581-1593. External link

Ahunon, L., Milano, F., Chevrier, A., & Lavertu, M. (2020). A novel image analysis algorithm reveals that media conditioned with chitosan and platelet-rich plasma biomaterial dose dependently increases fibroblast migration in a scratch assay. Biomedical Physics & Engineering Express, 6(6), 15 pages. External link

Zhang, H., Esquivel Guzman, J. A., Feng, X., Rivera, E., Lavertu, M., & Zhu, X. X. (2020). Protoporphyrin IX copolymer with poly(Ethylene glycol) methacrylate and its thermoresponsive properties. Canadian Journal of Chemistry, 98(9), 511-515. External link

2019

Ghazi Zadeh, L., Chevrier, A., Lamontagne, M., Buschmann, M. D., Hoemann, C. D., & Lavertu, M. (2019). Multiple platelet-rich plasma preparations can solubilize freeze-dried chitosan formulations to form injectable implants for orthopedic indications. Bio-Medical Materials and Engineering, 30(4), 349-364. External link

2018

Buschmann, M. D., Lavertu, M., Nelea, M., Darras, V., Alameh, M. G., Chevrier, A., Tran-Khanh, N., Naeini Tavakoli, A., & Veilleux, D. (2018). Coated chitosan-based polyplex for delivery of nucleic acids. (Patent Application no. US20180028458). External link

Chevrier, A., Darras, V., Picard, G., Nelea, M., Veilleux, D., Lavertu, M., Hoemann, C. D., & Buschmann, M. D. (2018). Injectable chitosan-platelet-rich plasma (PRP) implants to promote tissue regeneration: In vitro properties, in vivo residence, degradation, cell recruitment and vascularization. Journal of Tissue Engineering and Regenerative Medicine, 12(1), 217-228. External link

Veilleux, D., Gopalakrishna Panicker, R. K., Chevrier, A., Biniecki, K., Lavertu, M., & Buschmann, M. D. (2018). Lyophilisation and concentration of chitosan/siRNA polyplexes: Influence of buffer composition, oligonucleotide sequence, and hyaluronic acid coating. Journal of Colloid and Interface Science, 512, 335-345. External link

Alameh, M., Lavertu, M., Tran-Khanh, N., Chang, C.-Y., Lesage, F., Bail, M., Darras, V., Chevrier, A., & Buschmann, M. D. (2018). siRNA delivery with chitosan: influence of chitosan molecular weight, degree of deacetylation, and amine to phosphate ratio on in vitro silencing efficiency, hemocompatibility, biodistribution, and in vivo efficacy. Biomacromolecules, 19(1), 112-131. External link

2017

Fong, D., Gregoire-Gelinas, P., Cheng, A. P., Mezheritsky, T., Lavertu, M., Sato, S., & Hoemann, C. D. (2017). Lysosomal rupture induced by structurally distinct chitosans either promotes a type 1 IFN response or activates the inflammasome in macrophages. Biomaterials, 129, 127-138. Available

Tavakoli Naeini, A., Soliman, O. Y., Alameh, M. G., Lavertu, M., & Buschmann, M. D. (2017). Automated in-line mixing system for large scale production of chitosan-based polyplexes. Journal of Colloid and Interface Science, 500, 253-263. External link

Chevrier, A., Buschmann, M. D., Veilleux, D., Hoemann, C. D., & Lavertu, M. (2017). Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections. (Patent Application no. US20170049696). External link

Ouyang, W., Buschmann, M. D., Hoemann, C. D., Lavertu, M., & Chevrier, A. (2017). Novel formulation of physiological chitosan-inorganic salt solution/blood mixtures for tissue repair. (Patent Application no. US20170333477). External link

Pickenhahn, V., Grange, M., De Crescenzo, G., Lavertu, M., & Buschmann, M. D. (2017). Regioselective chitosan end-group activation: the triskelion approach. RSC Advances, 7(30), 18628-18638. Available

Ma, P. L., Lavertu, M., Winnik, F. M., & Buschmann, M. D. (2017). Stability and binding affinity of DNA/chitosan complexes by polyanion competition. Carbohydrate Polymers, 176, 167-176. External link

2016

Fong, D., Gregoire-Gelinas, P., Lavertu, M., Sato, S., & Hoemann, C. D. (2016, May). Human macrophages release higher IL-1ra over IL-1beta when stimulated by block acetylated chitosan microparticles and not by random acetylated chitosans or water-soluble oligomers [Poster]. 10th World Biomaterials Congress, Montréal, Québec. Published in Frontiers in Bioengineering and Biotechnology, 4. Available

Pickenhahn, V. D., Lavertu, M., Buschmann, M. D., De Crescenzo, G., & Darras, V. (2016). Conjugated chitosans and method of use and of making same. (Patent Application no. WO2016101068). External link

Buschmann, M. D., Lavertu, M., & Veilleux, D. (2016). Freeze-dried polyelectrolyte complexes that maintain size and biological activity. (Patent Application no. US20160130606). External link

Veilleux, D., Nelea, M., Biniecki, K., Lavertu, M., & Buschmann, M. D. (2016). Preparation of Concentrated Chitosan/DNA Nanoparticle Formulations by Lyophilization for Gene Delivery at Clinically Relevant Dosages. Journal of Pharmaceutical Sciences, 105(1), 88-96. External link

Thibault, M., Lavertu, M., Astolfi, M., & Buschmann, M. D. (2016). Structure Dependence of Lysosomal Transit of Chitosan-Based Polyplexes for Gene Delivery. Molecular Biotechnology, 58(10), 648-656. External link

2015

Pickenhahn, V., Darras, V., Dziopa, F., Biniecki, K., De Crescenzo, G., Lavertu, M., & Buschmann, M. D. (2015). Regioselective thioacetylation of chitosan end-groups for nanoparticle gene delivery systems. Chemical Science, 6(8), 4650. Available

2014

Alameh, M.-G., Lavertu, M., Merzouki, A., Biniecki, K., & Buschmann, M. D. (2014, May). Chitosan/siRNA nanoparticles demonstrate superior silencing efficiency and lower toxicity compared to lipid nanoparticles [Abstract]. 17th Annual Meeting of the American Society of Gene & Cell Therapy, Washington, DC. Published in Molecular Therapy, 22(S1). Available

Veilleux, D., Lavertu, M., Biniecki, K., & Buschmann, M. D. (2014, May). Lyophilized chitosan nanoparticles for pDNA and siRNA delivery: Physico-chemical properties, transfection efficiency, and cytotoxicity [Abstract]. American Society of Gene & Cell Therapy 17th Annual Meeting, Washington, DC. Published in Molecular Therapy, 22(S1). Available

Niebel, Y., Buschmann, M. D., Lavertu, M., & De Crescenzo, G. (2014). Combined Analysis of Polycation/ODN Polyplexes by Analytical Ultracentrifugation and Dynamic Light Scattering Reveals their Size, Refractive Index Increment, Stoichiometry, Porosity, and Molecular Weight. Biomacromolecules, 15(3), 940-947. External link

Tavakoli Naeini, A., Lavertu, M., Buschmann, M. D., & Biniecki, K. (2014, May). Large scale preparation of chitosan/nucleic acid nanoparticles using an automated inline mixing system [Abstract]. American Society of Gene & Cell Therapy 17th Annual Meeting, Washington, DC. Published in Molecular Therapy, 22. Available

2013

Hoemann, C. D., Guzmán-Morales, J., Tran-Khanh, N., Lavallée, G., Jolicoeur, M., & Lavertu, M. (2013). Chitosan rate of uptake in HEK293 cells is influenced by soluble versus microparticle state and enhanced by serum-induced cell metabolism and lactate-based media acidification. Molecules, 18(1), 1015-1035. Available

Buschmann, M. D., Merzouki, A., Lavertu, M., Thibault, M., Jean, M., & Darras, V. (2013). Chitosans for delivery of nucleic acids. Advanced Drug Delivery Reviews, 65(9), 1234-1270. External link

Chattopadhyahya, B., Sanon, N. T., Dominique, D. B., Lavertu, M., Berryer, M., Desgent, S., Salam, T., Carmant, L., & Dicristo, G. (2013, June). Hypoxia-Induced Seizures Affect Interneuronal Network Maturation in the Mouse Hippocampus and Neocortex [Paper]. 30th International Epilepsy Congress, Montréal, Canada. Published in Epilepsia, 54(S3). External link

Richard, I., Thibault, M., De Crescenzo, G., Buschmann, M. D., & Lavertu, M. (2013). Ionization behavior of chitosan and chitosan-DNA polyplexes indicate that chitosan has a similar capability to induce a proton-sponge effect as PEI. Biomacromolecules, 14(6), 1732-1740. External link

2012

Jean, M., Alameh, M., De Jesus, D., Thibault, M., Lavertu, M., Darras, V., Nelea, M., Buschmann, M. D., & Merzouki, A. (2012). Chitosan-Based Therapeutic Nanoparticles for Combination Gene Therapy and Gene Silencing of in Vitro Cell Lines Relevant to Type 2 Diabetes. European Journal of Pharmaceutical Sciences, 45(1-2), 138-149. External link

Lavertu, M., Darras, V., & Buschmann, M. D. (2012). Kinetics and efficiency of chitosan reacetylation. Carbohydrate Polymers, 87(2), 1192-1198. External link

Merzouki, A., Alameh, M., DeJesus, D., Jean, M., Darras, V., Thibault, M., Lavertu, M., & Buschmann, M. D. (2012). Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery. International Journal of Nanomedicine, 7, 1399-1414. Available

2011

Jean, M., Alameh, M., Daras, V., Lavertu, M., Thibault, M., Buschmann, M. D., & Merzouki, A. (2011, May). Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of Type 2 Diabetes [Paper]. 14th Annual Meeting American Society of Gene and Cell Therapy, Seattle, WA, USA. Unavailable

Jean, M., Alameh, M., Daras, V., Lavertu, M., Thibault, M., Buschmann, M. D., & Merzouki, A. (2011, May). Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of Type 2 Diabetes [Paper]. 1st Meeting of Canadian Chapter of The Controlled Release Society, Montréal, Québec, Canada. Unavailable

Thibault, M., Astolfi, M., Tran-Khanh, N., Lavertu, M., Darras, V., Merzouki, A., & Buschmann, M. D. (2011, May). Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes [Paper]. 1st Meeting of Canadian Chapter of The Controlled Release Society, Montréal, Québec. Unavailable

Thibault, M., Astolfi, M., Tran-Khanh, N., Lavertu, M., Darras, V., Merzouki, A., & Buschmann, M. D. (2011). Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes. Biomaterials, 32(20), 4639-4646. External link

Thibault, M., Astolfi, M., Lavertu, M., Darras, M., & Buschmann, M. D. (2011, May). The role and fate of excess polycations in efficient chitosan-based gene transfection [Paper]. 14th Annual Meeting American Society of Gene and Cell Therapy, Seattle, WA. Unavailable

2010

Nimesh, S., Thibault, M., Lavertu, M., & Buschmann, M. D. (2010). Enhanced gene delivery mediated by low molecular weight chitosan/DNA complexes: effect of pH and serum. Molecular Biotechnology, 46(2), 182-96. Available

Thibault, M., Nimesh, S., Lavertu, M., & Buschmann, M. D. (2010). Intracellular Trafficking and Decondensation Kinetics of Chitosan–pDNA Polyplexes. Molecular Therapy, 18(10), 1787-1795. Available

Thibault, M., Nimesh, S., Lavertu, M., & Buschmann, M. D. (2010, May). Intracellular trafficking and decondensation kinetics of chitosan-pDNA Polyplexes [Paper]. 13th Annual Meeting of American Society of Gene and Cell Therapy, Washington, DC. Unavailable

Buschmann, M. D., Thibault, M., Merzouki, A., Lavertu, M., Ma, P. L., Jean, M., Darras, V., & Winnik, F. M. (2010, May). Polynucleotide delivery with chitosans [Paper]. 93rd Canadian Chemistry Conference, Toronto, Ontario. Unavailable

2009

Jean, M., Smaoui, F., Lavertu, M., Methot, S., Bouhdoud, L., Buschmann, M. D., & Merzouki, A. (2009). Chitosan-Plasmid Nanoparticle Formulations for Im and Sc Delivery of Recombinant Fgf-2 and Pdgf-Bb or Generation of Antibodies. Gene Therapy, 16(9), 1097-1110. External link

Pei, L. M., Lavertu, M., Winnik, F. M., & Buschmann, M. D. (2009). New insights into chitosan-DNA interactions using isothermal titration microcalorimetry. Biomacromolecules, 10(6), 1490-1499. External link

Buschmann, M. D., Thibault, M., Merzouki, A., & Lavertu, M. (2009, August). Polynucleotide delivery with chitosans [Paper]. 8th World Congress of Chemical Engineering, Montréal, Québec. Unavailable

2008

Lavertu, M., Filion, D., & Buschmann, M. D. (2008). Heat-Induced Transfer of Protons From Chitosan to Glycerol Phosphate Produces Chitosan Precipitation and Gelation. Biomacromolecules, 9(2), 640-650. External link

Nelea, M., Lavertu, M., Ma, P. L., & Buschmann, M. D. (2008, May). Imaging of chitosan-plasmid DNA nanoparticles by scanning electron microscopy and atomic force microscopy [Paper]. Microscopical Society of Canada Meeting, Montréal, Québec. Unavailable

Thibault, M., Nimesh, S., Janta-Polanski, M., Lavertu, M., & Buschmann, M. D. (2008, October). Intercellular trafficking and dissociation kinetics of specific chitosan-pDNA polyplexes [Paper]. 6th International Nanomedicine and Drug Delivery Symposium, Toronto, ON, Canada. Unavailable

Ma, O., Lavertu, M., Sun, J., Nguyen, S., Buschmann, M. D., Winnik, F. M., & Hoemann, C. D. (2008). Precise Derivatization of Structurally Distinct Chitosans With Rhodamine B Isothiocyanate. Carbohydrate polymer, 72(4), 616-624. External link

2007

Lavertu, M. (2007). Caractérisation du système thermosensible chitosane-glycérol phosphate et applications pour la livraison de gènes [Ph.D. thesis, École Polytechnique de Montréal]. Available

Tran-Khanh, N., Lavertu, M., Hoemann, C. D., & Buschmann, M. D. (2007, February). Chondrocyte proliferation at the agarose-media interface resembles appositional mechanisms of the epiphyseal growth plate [Paper]. 53rd Annual Meeting of the Orthopaedic Research Society, San Diego, CA, USA. External link

Méthot, S., Lavertu, M., Sun, J., Smaoui, F., Jean, M., Merzouki, A., & Buschmann, M. D. (2007, September). Efficient in vivo gene delivery using chitosan/DNA nanoparticles for applications in cartilage repair [Paper]. 7th World Congress International Society for Cartilage Repair, Warsaw, Poland. External link

Filion, D., Lavertu, M., & Buschmann, M. D. (2007). Ionization and Solubility of Chitosan Solutions Related to Thermosensitive Chitosan/Glycerol-Phosphate Systems. Biomacromolecules, 8(10), 3224-3234. External link

Tran-Khanh, N., Lavertu, M., Lascau-Coman, V., Hoemann, C. D., & Buschmann, M. D. (2007, September). Time-lapse confocal imaging of living chondrocytes in appositionally developing outgrowths at the agarose-media interface [Paper]. 7th World Congress International Society for Cartilage Repair, Warsaw, Poland. External link

2006

Tran-Khanh, N., Lavertu, M., Hoemann, C. D., & Buschmann, M. D. (2006, October). Chondrocyte proliferation at the agarose-media interface resembles appositional mechanisms of the epiphyseal growth plate [Paper]. Transactions 56th Canadian Chemical Engineering Conference, Sherbrooke, QC. Unavailable

Hoemann, C. D., Ma, O., Lavertu, M., Lavalée, G., Sun, J., El-Gabalawy, H., Tran-Khanh, N., & Winnik, F. (2006, May). Controlled derivatization of chitosan with rhodamine B-isothiocyanate to study the influence of chitosan structure on stromal cell recognition and uptake [Paper]. Can Workshop on Pre-Clinical OA models, Montréal, Québec. Unavailable

Méthot, S., Lavertu, M., Ma, P. L., Winnik, F., & Buschmann, M. D. (2006, September). High Efficiency Gene Transfer Using Chitosan/DNA Nanoparticles With Specific Combinations of Molecular Weight and Degree of Deacetylation [Paper]. Transactions 10th International Conference on Chitin and Chitosan, Montpellier, France. Unavailable

Lavertu, M., Méthot, S., Tran-Khanh, N., & Buschmann, M. D. (2006). High Efficiency Gene Transfer Using Chitosan/DNA Nanoparticles With Specific Combinations of Molecular Weight and Degree of Deacetylation. Biomaterials, 27(27), 4815-4824. External link

Lavertu, M., Filion, D., Schmid, A., Zayani, M., & Buschmann, M. D. (2006, September). Studies on the mechanism of thermal gelation of chitosan-glycerol phosphate solutions [Paper]. Transactions 10th International Conference on Chitin and Chitosan, Montpellier, France. Unavailable

Lavertu, M., Filion, D., Schmid, A., Zayani, M., & Buschmann, M. D. (2006, October). Studies on the mechanism of thermal gelation of chitosan-glycerol phosphate solutions [Paper]. Transactions 56th Canadian Chemical Engineering Conference, Sherbrooke, Québec, Canada. Unavailable

2004

Filion, D., Lavertu, M., & Buschmann, M. D. (2004, June). Ionization-state dependent behavior of chitosan solutions : Theory and experiments [Paper]. Transactions Polyelectrolytes, Amherst, Massachusetts, USA. Unavailable

Lavertu, M., Methot, S., & Buschmann, M. D. (2004, June). Nanoparticules polymeres-ADN pour le transfert de gène [Paper]. Nanobiointerfaces pour les dispositifs intelligents, 17ième Entretiens du Centre Jacques Cartier, Montréal, Québec. Unavailable

2003

Lavertu, M., Xia, Z., Serreqi, A. N., Berrada, M., Rodrigues, A., Wang, D., Buschmann, M. D., & Gupta, A. (2003). A validated ¹H NMR method for the determination of the degree of deacetylation of chitosan. Journal of pharmaceutical and biomedical analysis, 32(6), 1149-1158. External link

2001

Buschmann, M. D., Garon, M., Ouellet, M., & Lavertu, M. (2001). Universal mechanical testing device. (Patent no. US6332364). External link

List generated on: Sun Oct 6 08:23:06 2024 EDT