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Design and construction of an optimized transmit/receive hybrid birdcage resonator to improve full body images of medium-sized animals in 7T scanner

Nibardo Lopez Rios, Philippe Pouliot, Konstantinos Papoutsis, Alexandru Foias, Nikola Stikov, Frédéric Lesage, Mathieu Dehaes and Julien Cohen-Adad

Article (2018)

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Abstract

The purpose of this work was to develop an optimized transmit/receive birdcage coil to extend the possibilities of a 7T preclinical MRI system to conduct improved full body imaging in medium-sized animals, such as large New Zealand rabbits. The coil was designed by combining calculation and electromagnetic simulation tools. The construction was based on precise mechanical design and careful building practice. A 16-leg, 20 cm long, 16 cm inner diameter, shielded quadrature hybrid structure was selected. Coil parameters were assessed on the bench and images were acquired on phantoms and rabbits. The results were compared to simulations and data obtained with an available commercial coil. An inexpensive assembly with an increase of 2 cm in useful inner diameter and 50 Omega matching with larger animals was achieved. A reduction in radiofrequency (RF) power demand of 31.8%, an improvement in image uniformity of 18.5 percentage points and an increase in signal-to-noise ratio of up to 42.2% were revealed by phantom image acquisitions, which was confirmed by in vivo studies. In conclusion, the proposed coil extended the possibilities of a preclinical 7T system as it improved image studies in relatively large animals by reducing the RF power demand, and increasing image uniformity and signal-to-noise ratio. Shorter scans and time under anesthesia or reduced RF exposure, resulting in better images and lower animal health risk during in vivo experiments, were achieved.

Uncontrolled Keywords

Animals; *Equipment Design; Magnetic Resonance Imaging/*instrumentation; Phantoms, Imaging; Rabbits

Subjects: 1900 Biomedical engineering > 1900 Biomedical engineering
1900 Biomedical engineering > 1901 Biomedical technology
Department: Department of Electrical Engineering
Funders: Canada Research Chair in Quantitative Magnetic Resonance Imaging (JCA), Canadian Institute of Health Research, Fonds de Recherche du Québec - Santé, Fonds de Recherche du Québec - Nature et Technologies, Natural Sciences and Engineering Research Council of Canada, Quebec BioImaging Network
Grant number: CIHR FDN-143263, 28826, 32600, 2015-PR-182754, 435897-2013, 2015- 04672, 5886
PolyPublie URL: https://publications.polymtl.ca/5008/
Journal Title: PLOS One (vol. 13, no. 2)
Publisher: PLOS
DOI: 10.1371/journal.pone.0192035
Official URL: https://doi.org/10.1371/journal.pone.0192035
Date Deposited: 17 Dec 2021 14:06
Last Modified: 17 May 2023 23:40
Cite in APA 7: Lopez Rios, N., Pouliot, P., Papoutsis, K., Foias, A., Stikov, N., Lesage, F., Dehaes, M., & Cohen-Adad, J. (2018). Design and construction of an optimized transmit/receive hybrid birdcage resonator to improve full body images of medium-sized animals in 7T scanner. PLOS One, 13(2), e0192035 (14 pages). https://doi.org/10.1371/journal.pone.0192035

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