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Blanquez-Yeste, V., Janelle, F., Tran, T., Ember, K., Sheehy, G., Dallaire, F., Marple, E., Urmey, K., Labidi, M., & Leblond, F. (2025). Development and preclinical evaluation of an endonasal Raman spectroscopy probe for transsphenoidal pituitary adenoma surgery. Journal of Biomedical Optics, 30(3), 035004 (17 pages). Available
Blanquez-Yeste, V., Janelle, F., Tran, T., Sheehy, G., Dallaire, F., Labidi, M., Cayrol, R., & Leblond, F. (2025, January). Development of an endonasal Raman spectroscopy probe for pituitary adenoma surgery [Paper]. Photonics West 2025, San Francisco, CA, USA (11 pages). External link
Dulude, J.-P., Le Moël, A., Dallaire, F., Doyon, J., Urmey, K., Marple, E., Leblanc, G., Basile, G., Mottard, S., Isler, M., Leblond, F., & Gervais, M.-K. (2025). Intraoperative use of high-speed Raman spectroscopy during soft tissue sarcoma resection. Scientific Reports, 15, 8789 (13 pages). Available
Daoust, F., Dallaire, F., Tavera, H., Ember, K., Guiot, M.-C., Petrecca, K., & Leblond, F. (2025). Preliminary study demonstrating cancer cells detection at the margins of whole glioblastoma specimens with Raman spectroscopy imaging. Scientific Reports, 15, 6453 (15 pages). Available
David, S., Tavera, H., Tran, T., Dallaire, F., Daoust, F., Tremblay, F., Richer, L., Meterissian, S., & Leblond, F. (2024). Macroscopic inelastic scattering imaging using a hyperspectral line-scanning system identifies invasive breast cancer in lumpectomy and mastectomy specimens. Journal of Biomedical Optics, 29(6), 065004 (16 pages). Available
David, S., Ksantini, N., Dallaire, F., Ember, K., Daoust, F., Sheehy, G., Hadjipanayis, C. G., Petrecca, K., Wilson, B. C., & Leblond, F. (2024). Toward noncontact macroscopic imaging of multiple cancers using multi-spectral inelastic scattering detection. Journal of Biophotonics, 2024000087 (7 pages). External link
Daoust, F., Tavera, H., Dallaire, F., Orsini, P., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (2023). A clinical Raman spectroscopy imaging system and safety requirements for in situ intraoperative tissue characterization. Analyst, 148(9), 1991-2001. External link
David, S., Tran, T., Dallaire, F., Sheehy, G., Azzi, F., Trudel, D., Tremblay, F., Ömeroğlu, A., Leblond, F., & Meterissian, S. (2023). In situ Raman spectroscopy and machine learning unveil biomolecular alterations in invasive breast cancer. Journal of Biomedical Optics, 28(3), 036009 (18 pages). External link
David, S., Plante, A., Dallaire, F., Tremblay, J.-P., Sheehy, G., Macdonald, E., Forrest, L., Daneshmand, M., Trudel, D., Wilson, B. C., Hopkins, L., Murugkar, S., Vanderhyden, B., & Leblond, F. (2022). Multispectral label-free Raman spectroscopy can detect ovarian and endometrial cancer with high accuracy. Journal of Biophotonics, 15(2), 10 pages. External link
Dallaire, F., Picot, F., Tremblay, J.-P., Sheehy, G., Lemoine, É., Agarwal, R., Kadoury, S., Trudel, D., Lesage, F., Petrecca, K., & Leblond, F. (2020). Quantitative spectral quality assessment technique validated using intraoperative in vivo Raman spectroscopy measurements. Journal of Biomedical Optics, 25(4). Available
Ember, K., Dallaire, F., D'Amours, É., Bounaas, M., Selb, J., Lesage, F., & Leblond, F. (2025, April). Low-cost Raman Spectroscopy for Detection of Lung Cancer in a National Blood Plasma Biobank [Paper]. Clinical and Translational Biophotonics 2025, Coronado, CA, USA. External link
Ember, K. J. I., Ksantini, N., Dallaire, F., Sheehy, G., Tran, T., Dehaes, M., Durand, M., Trudel, D., & Leblond, F. (2024). Liquid saliva-based Raman spectroscopy device with on-board machine learning detects COVID-19 infection in real-time. The Analyst, 149(22), 5535-5545. Available
Ember, K., Dallaire, F., Plante, A., Sheehy, G., Guiot, M.-C., Agarwal, R., Yadav, R., Douet, A., Selb, J., Tremblay, J. P., Dupuis, A., Marple, E., Urmey, K., Rizea, C., Harb, A., McCarthy, L., Schupper, A., Umphlett, M., Tsankova, N., ... Petrecca, K. (2024). In situ brain tumor detection using a Raman spectroscopy system — results of a multicenter study. Scientific Reports, 14, 14 (12 pages). Available
Ember, K., Ksantini, N., Dallaire, F., Sheehy, G., Noé, A., Tran, T., Durand, M., Trudel, D., & Leblond, F. (2024, January). Rapid detection of COVID-19 in liquid saliva using reagent-free Raman spectroscopy [Presentation]. In SPIE Photonics West 2024, San Francisco, California, United States. External link
Ember, K., Daoust, F., Mahfoud, M., Dallaire, F., Ahmad, E. Z., Tran, T., Plante, A., Diop, M.-K., Nguyen, T., St-Georges-Robillard, A., Ksantini, N., Lanthier, J., Filiatrault, A., Sheehy, G., Beaudoin, G., Quach, C., Trudel, D., & Leblond, F. (2022). Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning. Journal of Biomedical Optics, 27(2), 025002 (24 pages). Available
Grajales Lopera, D. O., Le, W., Blanquez-Yeste, V., Dallaire, F., Azzi, F., Delouya, G., Trudel, D., Leblond, F., Ménard, C., & Kadoury, S. (2025). Deployment of a real-time prostate cancer confirmation system with Raman spectroscopy: fine-tuning versus test-time adaptation of 1D CNNs. Biophotonics discovery., 2(03). External link
Grajales, D., Le, W. T., Tran, T., David, S., Dallaire, F., Ember, K., Leblond, F., Menard, C., & Kadoury, S. (2024). Robot-assisted biopsy sampling for online Raman spectroscopy cancer confirmation in the operating room. International Journal of Computer Assisted Radiology and Surgery, 9-9. External link
Grajales, D., Le, W., Dallaire, F., Sheehy, G., David, S., Tran, T., Leblond, F., Ménard, C., & Kadoury, S. (2023, October). Towards Real-Time Confirmation of Breast Cancer in the OR Using CNN-Based Raman Spectroscopy Classification [Paper]. 2nd International Workshop on Cancer Prevention Through Early Detection (CaPTion 2023), Vancouver, BC, Canada. External link
Grosset, A.-A., Dallaire, F., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., Van Der Kwast, T., Orain, M., ... Trudel, D. (2020). Data from: Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation [Dataset]. External link
Grosset, A.-A., Dallaire, F., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., van der Kwast, T., Orain, M., ... Trudel, D. (2020). Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation. Plos Medicine, 17(8), e1003281 (20 pages). External link
Košík, I., Dallaire, F., Pires, L., Tran, T., Leblond, F., & Wilson, B. (2023). Preclinical evaluation of Raman spectroscopy for pedicular screw insertion surgical guidance in a porcine spine model. Journal of Biomedical Optics, 28(5), 057003 (15 pages). External link
Leblond, F., Dallaire, F., Ember, K., Le Moël, A., Blanquez-Yeste, V., Tavera, H., Sheehy, G., Trang, T., Guiot, M.-C., Weil, A. G., Dudley, R., Hadjipanayis, C. G., & Petrecca, K. (2025). Quantitative assessment of the generalizability of a brain tumor Raman spectroscopy machine learning model to various tumor types including astrocytoma and oligodendroglioma [Discussion or Letter]. Journal of Biomedical Optics, 30(1), 010501 (7 pages). Available
Leblond, F., Dallaire, F., Trang, T., Yadav, R., Aubertin, K., Goudie, E., Roméo, P., Kent, C., Leduc, C., & Liberman, M. (2023). Subsecond lung cancer detection within a heterogeneous background of normal and benign tissue using single-point Raman spectroscopy. Journal of Biomedical Optics, 28(9), 090501 (8 pages). Available
Lopera, D. O. G., Picot, F., Shams, R., Dallaire, F., Sheehy, G., Alley, S., Barkati, M., Delouya, G., Carrier, J.-F., Birlea, M., Trudel, D., Leblond, F., Ménard, C., & Kadoury, S. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model combining spectral and MRI-radiomics features. Journal of Biomedical Optics, 27(9), 095004 (16 pages). External link
Lemoine, É., Dallaire, F., Yadav, R., Agarwal, R., Kadoury, S., Trudel, D., Guiot, M.-C., Petrecca, K., & Leblond, F. (2019). Feature engineering applied to intraoperative in vivo Raman spectroscopy sheds light on molecular processes in brain cancer: a retrospective study of 65 patients. Analyst, 144(22), 6517-6532. External link
Orsini, P., Desroches, J., Daoust, F., Tavera, H., Dallaire, F., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (2023, January). Raman macroscopic imaging system for intraoperative brain cancer detection [Paper]. SPIE BiOS 2023, San Francisco, California. External link
Picot, F., Shams, R., Dallaire, F., Sheehy, G., Tran, T., Grajales, D., Birlea, M., Trudel, D., Ménard, C., Kadoury, S., & Leblond, F. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 1: Raman spectroscopy fiber-optics system and in situ tissue characterization. Journal of Biomedical Optics, 27(9), 095003 (14 pages). External link
Plante, A., Dallaire, F., Grosset, A.-A., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., Van Der Kwast, T., ... Leblond, F. (2021). Dimensional reduction based on peak fitting of Raman micro spectroscopy data improves detection of prostate cancer in tissue specimens. Journal of Biomedical Optics, 26(11), 14 pages. External link
Picot, F., Daoust, F., Sheehy, G., Dallaire, F., Chaikho, L., Bégin, T., Kadoury, S., & Leblond, F. (2020). Data consistency and classification model transferability across biomedical Raman spectroscopy systems. Translational Biophotonics, 3(1), 1-11. Available
Picot, F., Sheehy, G., Dallaire, F., Tremblay, J.-P., Daoust, F., Lemoine, É., Chaikho, L., Bégin, T., Petrecca, K., Kadoury, S., Leblond, F., Elson, D. S., Gioux, S., & Pogue, B. W. (2020, April). Data compatibility across point probe Raman spectroscopy systems and its impact on statistical models portability (Conference Presentation) [Presentation]. In Clinical Biophotonics 2020. External link
Pinto, M., Zorn, K. C., Tremblay, J.-P., Desroches, J., Dallaire, F., Aubertin, K., Marple, E., Kent, C., Leblond, F., Trudel, D., & Lesage, F. (2019). Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures. Journal of Biomedical Optics, 24(2), 025001 (10 pages). Available
Sheehy, G., Picot, F., Dallaire, F., Ember, K., Nguyen, T., Petrecca, K., Trudel, D., & Leblond, F. (2023). Open-sourced Raman spectroscopy data processing package implementing a baseline removal algorithm validated from multiple datasets acquired in human tissue and biofluids. Journal of Biomedical Optics, 28(2), 025002 (20 pages). External link
Shams, R., Picot, F., Grajales, D., Sheehy, G., Dallaire, F., Birlea, M., Saad, F., Trudel, D., Ménard, C., Leblond, F., & Kadoury, S. (2020). Pre-clinical evaluation of an image-guided in-situ Raman spectroscopy navigation system for targeted prostate cancer interventions. International Journal of Computer Assisted Radiology and Surgery, 15(5), 867-876. External link
Tran, T., Dallaire, F., Sonnen, J. A., Cayrol, R., Leblond, F., & Dudley, R. W. R. (2025). Single-cell raman spectroscopy detects pediatric focal cortical dysplasia. Biophotonics Discovery, 2(1), 015002 (12 pages). Available
