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Low-Power Implantable Device for Onset Detection and Subsequent Treatment of Epileptic Seizures: A Review

Muhammad Tariqus Salam, Mohamad Sawan and Dang Khoa Nguyen

Article (2010)

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Over the past few years, there has been growing interest in neuro-responsive intracerebral local treatments of seizures, such as focal drug delivery, focal cooling, or electrical stimulation. This mode of treatment requires an effective intracerebral electroencephalographic acquisition system, seizure detector, brain stimulator, and wireless system that consume ultra-low power. This review focuses on alternative brain stimulation treatments for medically intractable epilepsy patients. We mainly discuss clinical studies of long-term responsive stimulation and suggest safer optimized therapeutic options for epilepsy. Finally, we conclude our study with the proposed low-power, implantable fully integrated device that automatically detects low-voltage fast activity ictal onsets and triggers focal treatment to disrupt seizure progression. The detection performance was verified using intracerebral electroencephalographic recordings from two patients with epilepsy. Further experimental validation of this prototype is underway.

Subjects: 1900 Biomedical engineering > 1900 Biomedical engineering
2500 Electrical and electronic engineering > 2500 Electrical and electronic engineering
9000 Health sciences > 9000 Health sciences
Department: Department of Electrical Engineering
Research Center: Other
Polystim - Neurotechnology Laboratory
Funders: CRSNG/NSERC, Canada Research Chair in Smart Medical Devices, Microsystems Strategic Alliance of Québec (ReSMiQ)
PolyPublie URL: https://publications.polymtl.ca/3400/
Journal Title: Journal of Healthcare Engineering (vol. 1, no. 2)
Publisher: Hindawi
DOI: 10.1260/2040-2295.1.2.169
Official URL: https://doi.org/10.1260/2040-2295.1.2.169
Date Deposited: 10 Jan 2019 13:42
Last Modified: 11 Apr 2024 11:48
Cite in APA 7: Salam, M. T., Sawan, M., & Nguyen, D. K. (2010). Low-Power Implantable Device for Onset Detection and Subsequent Treatment of Epileptic Seizures: A Review. Journal of Healthcare Engineering, 1(2), 169-184. https://doi.org/10.1260/2040-2295.1.2.169


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