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Low-Power Implantable Device for Onset Detection and Subsequent Treatment of Epileptic Seizures: A Review

Muhammad Salam, Mohamad Sawan and Dang Nguyen

Article (2010)

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Cite this document: Salam, M., Sawan, M. & Nguyen, D. (2010). Low-Power Implantable Device for Onset Detection and Subsequent Treatment of Epileptic Seizures: A Review. Journal of Healthcare Engineering, 1(2), p. 169-184. doi:10.1260/2040-2295.1.2.169
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Over the past few years, there has been growing interest in neuro-responsive intracerebral local treatments of seizures, such as focal drug delivery, focal cooling, or electrical stimulation. This mode of treatment requires an effective intracerebral electroencephalographic acquisition system, seizure detector, brain stimulator, and wireless system that consume ultra-low power. This review focuses on alternative brain stimulation treatments for medically intractable epilepsy patients. We mainly discuss clinical studies of long-term responsive stimulation and suggest safer optimized therapeutic options for epilepsy. Finally, we conclude our study with the proposed low-power, implantable fully integrated device that automatically detects low-voltage fast activity ictal onsets and triggers focal treatment to disrupt seizure progression. The detection performance was verified using intracerebral electroencephalographic recordings from two patients with epilepsy. Further experimental validation of this prototype is underway.

Open Access document in PolyPublie
Subjects: 1900 Génie biomédical > 1900 Génie biomédical
2500 Génie électrique et électronique > 2500 Génie électrique et électronique
9000 Sciences de la santé > 9000 Sciences de la santé
Department: Département de génie électrique
Research Center: Autre
Funders: CRSNG/NSERC, Canada Research Chair in Smart Medical Devices, Microsystems Strategic Alliance of Québec (ReSMiQ)
Date Deposited: 10 Jan 2019 13:42
Last Modified: 11 Jan 2019 01:20
PolyPublie URL: https://publications.polymtl.ca/3400/
Document issued by the official publisher
Journal Title: Journal of Healthcare Engineering (vol. 1, no. 2)
Publisher: Hindawi
Official URL: https://doi.org/10.1260/2040-2295.1.2.169


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