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Merzouki, A., & Buschmann, M. D. (2017). Compositions and methods for efficacious and safe delivery of siRNA using specific chitosan-based nanocomplexes. (Patent no. US9809821). External link
Alameh, M.-G., Lavertu, M., Merzouki, A., Biniecki, K., & Buschmann, M. D. (2014, May). Chitosan/siRNA nanoparticles demonstrate superior silencing efficiency and lower toxicity compared to lipid nanoparticles [Abstract]. 17th Annual Meeting of the American Society of Gene & Cell Therapy, Washington, DC. Published in Molecular Therapy, 22(S1). Available
Jean, M., Jeandupeux, D., Merzouki, A., & Buschmann, M. D. (2014, May). Combining delivery of GLP-1 gene expressing plasmid and DPP-4 gene silencing siRNA using Chitosan-based nanoparticles for Type-2 Diabetes treatment [Abstract]. 17th Annual Meeting of the American Society of Gene & Cell Therapy, Washington, DC (1 page). Published in Molecular Therapy, 22(S1). Available
Jean, M., Derbali, R., DeJesus, D., Jeandupeux, D., Merzouki, A., & Buschmann, M. D. (2014, May). Apolipoprotein B knock-down by Chitosan/ApoB-siRNA nanoparticles lowers plasma cholesterol in atherosclerosis mouse model [Abstract]. 17th Annual Meeting of the American Society of Gene & Cell Therapy, Washington, DC (1 page). Published in Molecular Therapy, 22(S1). Available
Jean, M., Behhammadi, M., Sidique, A., Jeandupeux, D., Merzouki, A., & Buschmann, M. D. (2014, May). P-Glycoprotein knock-down by Chitosan/Mdr1-siRNA nanoparticles increases sensitivity to chemotherapeutics [Abstract]. 17th Annual Meeting of the American Society of Gene & Cell Therapy, Washington, DC (1 page). Published in Molecular Therapy, 22(S1). Available
Buschmann, M. D., Merzouki, A., Lavertu, M., Thibault, M., Jean, M., & Darras, V. (2013). Chitosans for delivery of nucleic acids. Advanced Drug Delivery Reviews, 65(9), 1234-1270. External link
Merzouki, A., & Buschmann, M. D. (2013). Gene therapy for diabetes with chitosan-delivered plasmid encoding glucagon-like peptide 1. (Patent Application no. US20130210717). External link
Liberelle, B., Merzouki, A., & De Crescenzo, G. (2013). Immobilized Carboxymethylated Dextran Coatings for Enhanced ELISA. Journal of Immunological Methods, 389(1-2), 38-44. External link
Merzouki, A., Buschmann, M. D., Jean, M., Young, R. S., Liao, S., Gal, S., Li, Z., & Slilaty, S. N. (2012). Adva-27a, a Novel Podophyllotoxin Derivative Found to Be Effective Against Multidrug Resistant Human Cancer Cells. Anticancer Research, 32(10), 4423-4432. External link
Jean, M., Alameh, M., De Jesus, D., Thibault, M., Lavertu, M., Darras, V., Nelea, M., Buschmann, M. D., & Merzouki, A. (2012). Chitosan-Based Therapeutic Nanoparticles for Combination Gene Therapy and Gene Silencing of in Vitro Cell Lines Relevant to Type 2 Diabetes. European Journal of Pharmaceutical Sciences, 45(1-2), 138-149. External link
Merzouki, A., Alameh, M., DeJesus, D., Jean, M., Darras, V., Thibault, M., Lavertu, M., & Buschmann, M. D. (2012). Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery. International Journal of Nanomedicine, 7, 1399-1414. Available
Alameh, M., DeJesus, D., Benhamadi, M., Jean, M., Buschmann, M. D., & Merzouki, A. (2011, May). Chitosan nanoparticulate system for the delivery of siRNA targeting genome caretakers for the development of potential cancer therapies [Paper]. 1st Meeting of Canadian Chapter of The Controlled Release Society, Montréal, Québec. Unavailable
Jean, M., Alamech, M., Buschmann, M. D., & Merzouki, A. (2011). Effective and safe gene-based delivery of GLP using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of diabetes. Gene Therapy, 18(8), 807-816. External link
Jean, M., Alameh, M., Daras, V., Lavertu, M., Thibault, M., Buschmann, M. D., & Merzouki, A. (2011, May). Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of Type 2 Diabetes [Paper]. 14th Annual Meeting American Society of Gene and Cell Therapy, Seattle, WA, USA. Unavailable
Jean, M., Alameh, M., Daras, V., Lavertu, M., Thibault, M., Buschmann, M. D., & Merzouki, A. (2011, May). Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of Type 2 Diabetes [Paper]. 1st Meeting of Canadian Chapter of The Controlled Release Society, Montréal, Québec, Canada. Unavailable
Thibault, M., Astolfi, M., Tran-Khanh, N., Lavertu, M., Darras, V., Merzouki, A., & Buschmann, M. D. (2011, May). Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes [Paper]. 1st Meeting of Canadian Chapter of The Controlled Release Society, Montréal, Québec. Unavailable
Thibault, M., Astolfi, M., Tran-Khanh, N., Lavertu, M., Darras, V., Merzouki, A., & Buschmann, M. D. (2011). Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes. Biomaterials, 32(20), 4639-4646. External link
DeJesus, D., Alameh, M., Jean, M., Lascau, V., Buschmann, M. D., & Merzouki, A. (2011, May). Therapeutic lowering of circulating ApoB in atherosclerotic mice by intravenous administration of chitosan-siRNA nanoparticles [Paper]. 1st Meeting of Canadian Chapter of The Controlled Release Society, Montréal, Québec. Unavailable
Alamech, M., Jean, M., DeJesus, D., Buschmann, M. D., & Merzouki, A. (2010). Chitosanase-based method for RNA isolation from cells transfected with chitosan/siRNA nanocomplexes for real-time RT-PCR in gene silencing. International Journal of Nanomedicine, 5, 473-481. Available
Sabbahi, R., Lavallée, R., Merzouki, A., & Guertin, C. (2010). Differentiation of entomopathogenic fungus Beauveria bassiana (Ascomycetes: Hypocreales) isolates by PCR-RFLP. [Différentiation d’isolats du champignon entomopathogène Beauveria bassiana (Ascomycetes : Hypocreales) par PCR-RFLP]. Phytoprotection, 90(2), 49-56. External link
Liberelle, B., Bartholin, L., Boucher, C., Murschel, F., Jolicoeur, M., Durocher, Y., Merzouki, A., & De Crescenzo, G. (2010). New Elisa Approach Based on Coiled-Coil Interactions. Journal of Immunological Methods, 362(1-2), 161-167. External link
Buschmann, M. D., Thibault, M., Merzouki, A., Lavertu, M., Ma, P. L., Jean, M., Darras, V., & Winnik, F. M. (2010, May). Polynucleotide delivery with chitosans [Paper]. 93rd Canadian Chemistry Conference, Toronto, Ontario. Unavailable
Jean, M., Smaoui, F., Lavertu, M., Methot, S., Bouhdoud, L., Buschmann, M. D., & Merzouki, A. (2009). Chitosan-Plasmid Nanoparticle Formulations for Im and Sc Delivery of Recombinant Fgf-2 and Pdgf-Bb or Generation of Antibodies. Gene Therapy, 16(9), 1097-1110. External link
Buschmann, M. D., Thibault, M., Merzouki, A., & Lavertu, M. (2009, August). Polynucleotide delivery with chitosans [Paper]. 8th World Congress of Chemical Engineering, Montréal, Québec. Unavailable
Méthot, S., Lavertu, M., Sun, J., Smaoui, F., Jean, M., Merzouki, A., & Buschmann, M. D. (2007, September). Efficient in vivo gene delivery using chitosan/DNA nanoparticles for applications in cartilage repair [Paper]. 7th World Congress International Society for Cartilage Repair, Warsaw, Poland. External link
Smaoui, F., Buschmann, M. D., Jean, M., Bouhdoud, L., Henrichon, M., Méthot, S., & Merzouki, A. (2006, June). The chitosan used as a delivery system of therapeutic growth factors for the induction of cartilage regeneration [Paper]. Canadian Society of Microbiologists Annual Conference, London, Ontario. Unavailable
