Polymer blends as a route for controlled drug release

Abstract

Controlled drug delivery -- Polymer structure and drug delivery -- Research objectives -- Drug delivery -- Bovine serum albumin (BSA) -- Spectrophotometry -- Co-continuous structure and its controlling parameters -- Drug encapsulation techniques -- Diffusion (diffusion coefficient calculation & drug release kinetics) -- Drug dissolution -- Burst release -- Incomplete release -- Encapsulation efficiency -- Closed-cell formulation -- Polyelectrolytes -- Materials -- HDPE and PLA porous device preparation -- Morphology analysis with scanning electron microscopy (SEM) -- Characterization of HDPE and PLA highly co-continuous structures -- Loading protocol and loading efficacy calculation -- Layer-by-layer deposition of polyelectrolytes inside the HDPE and PLA porous structures -- In vitro BSA release -- Article presentation -- Porous devices derived from co-continuous blends as a route for controlled drug release.

Uncontrolled Keywords

Médicaments polymères -- Effet retard; Capsules (Pharmacie); Médicaments-retard