Nicolas Guérin, Martin Lévesque et Daniel Therriault
Article de revue (2014)
|
Libre accès au plein texte de ce document Version officielle de l'éditeur Conditions d'utilisation: Creative Commons: Attribution (CC BY) Télécharger (1MB) |
Abstract
This paper reports the fabrication and testing of a helical cell separator that uses insulator-based dielectrophoresis as the driving force of its separation. The helical channel shape's main advantage is its constant curvature radius which generates a constant electric field gradient. The presented separator was fabricated by extruding a sacrificial ink on rotating spindles using a computer- controlled robot. After being assembled, connected to the reservoir and encapsulated in epoxy resin, the ink was removed to create a helical microchannel. The resulting device was tested by circulating polystyrene microbeads of 4 and 10 μm diameter through its channel using a voltage of 900 VDC. The particles were separated with efficiencies of 94.0% and 92.5%, respectively. However, roughness in some parts of the channel and connections that had larger diameters compared to the channel created local electric field gradients which, doubtless, hindered separation. It is a promising device that could lead the way toward portable and affordable medical devices.
Mots clés
| Département: | Département de génie mécanique |
|---|---|
| Centre de recherche: | LM2 - Laboratoire de Mécanique Multi-échelles |
| URL de PolyPublie: | https://publications.polymtl.ca/4910/ |
| Titre de la revue: | Journal of Biomedical Science and Engineering (vol. 7, no 9) |
| Maison d'édition: | Scientific Research Publishing Inc. |
| DOI: | 10.4236/jbise.2014.79064 |
| URL officielle: | https://doi.org/10.4236/jbise.2014.79064 |
| Date du dépôt: | 19 avr. 2022 14:06 |
| Dernière modification: | 07 avr. 2025 14:40 |
| Citer en APA 7: | Guérin, N., Lévesque, M., & Therriault, D. (2014). Helical dielectrophoretic particle separator fabricated by conformal spindle printing. Journal of Biomedical Science and Engineering, 7(9), 641-650. https://doi.org/10.4236/jbise.2014.79064 |
|---|---|
Statistiques
Total des téléchargements à partir de PolyPublie
Téléchargements par année
Provenance des téléchargements
Dimensions
