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Automatic screening and grading of age-related macular degeneration from texture analysis of fundus images

Thanh Vân Phan, Lama Seoud, Hadi Chakor and Farida Cheriet

Article (2016)

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Cite this document: Phan, T. V., Seoud, L., Chakor, H. & Cheriet, F. (2016). Automatic screening and grading of age-related macular degeneration from texture analysis of fundus images. Journal of Ophthalmology, 2016, p. 1-11. doi:10.1155/2016/5893601
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Age-related macular degeneration (AMD) is a disease which causes visual deficiency and irreversible blindness to the elderly. In this paper, an automatic classification method for AMD is proposed to perform robust and reproducible assessments in a telemedicine context. First, a study was carried out to highlight the most relevant features for AMD characterization based on texture, color, and visual context in fundus images. A support vector machine and a random forest were used to classify images according to the different AMD stages following the AREDS protocol and to evaluate the features' relevance. Experiments were conducted on a database of 279 fundus images coming from a telemedicine platform. The results demonstrate that local binary patterns in multiresolution are the most relevant for AMD classification, regardless of the classifier used. Depending on the classification task, our method achieves promising performances with areas under the ROC curve between 0.739 and 0.874 for screening and between 0.469 and 0.685 for grading. Moreover, the proposed automatic AMD classification system is robust with respect to image quality.

Open Access document in PolyPublie
Subjects: 1900 Génie biomédical > 1900 Génie biomédical
2700 Technologie de l'information > 2706 Génie logiciel
Department: Département de génie informatique et génie logiciel
Institut de génie biomédical
Research Center: Non applicable
Funders: Diagnos Inc., CRSNG/NSERC
Date Deposited: 09 Jan 2019 12:33
Last Modified: 08 Apr 2021 10:43
PolyPublie URL: https://publications.polymtl.ca/3507/
Document issued by the official publisher
Journal Title: Journal of Ophthalmology (vol. 2016)
Publisher: Hindawi
Official URL: https://doi.org/10.1155/2016/5893601


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