<  Back to the Polytechnique Montréal portal

A Feasibility Study for Microwave Breast Cancer Detection Using Contrast-Agent-Loaded Bacterial Microbots

Panagiotis Kosmas, Yifan Chen and Sylvain Martel

Article (2013)

Open Acess document in PolyPublie and at official publisher
[img]
Preview
Open Access to the full text of this document
Published Version
Terms of Use: Creative Commons Attribution
Download (3MB)
Show abstract
Hide abstract

Abstract

We propose a new approach to microwave breast tumor sensing and diagnosis based on the use of biocompatible flagellated magnetotactic bacteria (MTB) adapted to operate in human microvasculature. It has been verified experimentally by Martel et al. that externally generated magnetic gradients could be applied to guide the MTB along preplanned routes inside the human body, and a nanoload could be attached to these bacterial microbots. Motivated by these useful properties, we suggest loading a nanoscale microwave contrast agent such as carbon nanotubes (CNTs) or ferroelectric nanoparticles (FNPs) onto the MTB in order to modify the dielectric properties of tissues near the agent-loaded bacteria. Subsequently, we propose a novel differential microwave imaging (DMI) technique to track simultaneously multiple swarms of MTB microbots injected into the breast. We also present innovative strategies to detect and localize a breast tissue malignancy and estimate its size via this DMI-trackable bacterial microrobotic system. Finally, we use an anatomically realistic numerical breast phantom as a platform to demonstrate the feasibility of this tumor diagnostic method.

Subjects: 2500 Electrical and electronic engineering > 2500 Electrical and electronic engineering
2500 Electrical and electronic engineering > 2520 Microwave and millimeter-wave devices, circuits and technologies
9000 Health sciences > 9000 Health sciences
Department: Department of Computer Engineering and Software Engineering
Funders: 2013 Guangdong Natural Science Funds for Distinguished Young Scholar
Grant number: S2013050014223
PolyPublie URL: https://publications.polymtl.ca/3435/
Journal Title: International Journal of Antennas and Propagation (vol. 2013)
Publisher: Hindawi
DOI: 10.1155/2013/309703
Official URL: https://doi.org/10.1155/2013/309703
Date Deposited: 14 Dec 2018 16:20
Last Modified: 01 Nov 2023 13:11
Cite in APA 7: Kosmas, P., Chen, Y., & Martel, S. (2013). A Feasibility Study for Microwave Breast Cancer Detection Using Contrast-Agent-Loaded Bacterial Microbots. International Journal of Antennas and Propagation, 2013, 1-11. https://doi.org/10.1155/2013/309703

Statistics

Total downloads

Downloads per month in the last year

Origin of downloads

Dimensions

Repository Staff Only

View Item View Item