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Coordination strategies to improve COVID-19 PCR laboratory testing scale up in Nepal: An analysis

Hannah Bakker, Govindakarnavar Arunkumar, Parvathy Krishnan Krishnakumari, Joaquim Gromicho, Fannie L. Côté, Nadia Lahrichi, Priya Jha, Saugat Shrestha, Rashmi Mulmi, Nirajan Bhusal, Deepesh Stapith, Runa Jha, Lilee Shrestha, Dhamari Naidoo, Reuben Samuel and Victor del Rio Vilas

Article (2024)

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Abstract

During the COVID-19 pandemic, Nepal rapidly expanded its PCR testing capacity, essential for effective outbreak response. However, many laboratories faced overwhelming test volumes, resulting in delays that may have hindered containment efforts. This study aims to determine whether these challenges stemmed from capacity limitations and/or imbalanced sample distribution due to inadequate coordination. In this retro-perspective simulation of SARS-CoV-2 testing in Nepal during 2021, we evaluate the impact of coordinated sample transfers on reducing laboratory stress and wait times during demand peaks. Our findings reveal that centralized coordination and strategic partnerships for sample transfers significantly enhance diagnostic network performance, even under high demand. These insights offer valuable guidance for policymakers on implementing effective coordination strategies to strengthen diagnostic networks for future pandemics.

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Department: Department of Mathematics and Industrial Engineering
Research Center: CIRRELT - Interuniversity Research Centre on Enterprise Networks, Logistics and Transportation
Funders: UNICEF/UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases (TDR)
PolyPublie URL: https://publications.polymtl.ca/61020/
Journal Title: PLoS ONE (vol. 19, no. 12)
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0314746
Official URL: https://doi.org/10.1371/journal.pone.0314746
Date Deposited: 09 Dec 2024 11:36
Last Modified: 30 Jan 2026 15:40
Cite in APA 7: Bakker, H., Arunkumar, G., Krishnakumari, P. K., Gromicho, J., Côté, F. L., Lahrichi, N., Jha, P., Shrestha, S., Mulmi, R., Bhusal, N., Stapith, D., Jha, R., Shrestha, L., Naidoo, D., Samuel, R., & del Rio Vilas, V. (2024). Coordination strategies to improve COVID-19 PCR laboratory testing scale up in Nepal: An analysis. PLoS ONE, 19(12), e0314746-e0314746. https://doi.org/10.1371/journal.pone.0314746

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