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Wavelength shift in a whispering gallery microdisk due to bacterial sensing: a theoretical approach

Hala Ghali, Pablo Bianucci and Yves-Alain Peter

Article (2017)

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Abstract

Whispering gallery mode microcavities have recently been studied as a means to achieve real-time label-free detection of biological targets such as virus particles, specific DNA sequences, or proteins. Binding of a biomolecule to the surface of a microresonator will increase its path length, leading to a shift in the resonance frequency according to the reactive sensing principle. In this paper, we develop a theoretical expression that will link the reactive shift to the bacteria and microdisk parameters and help quantify the number of bacteria that bind to the surface of a 200μm-diameter silica microdisk.

Uncontrolled Keywords

Optical microdisk; Wavelength shift; Bacterial sensing

Subjects: 1900 Biomedical engineering > 1901 Biomedical technology
5200 Microbiology > 5200 Microbiology
9000 Health sciences > 9000 Health sciences
Department: Department of Engineering Physics
Funders: CRSNG/NSERC, CMC microsystems
Grant number: Strategic Grant 365207-2008, 812, 837, 2976
PolyPublie URL: https://publications.polymtl.ca/3589/
Journal Title: Sensing and Bio-Sensing Research (vol. 13)
Publisher: Elsevier
DOI: 10.1016/j.sbsr.2017.01.004
Official URL: https://doi.org/10.1016/j.sbsr.2017.01.004
Date Deposited: 03 Apr 2020 10:04
Last Modified: 09 Apr 2024 03:13
Cite in APA 7: Ghali, H., Bianucci, P., & Peter, Y.-A. (2017). Wavelength shift in a whispering gallery microdisk due to bacterial sensing: a theoretical approach. Sensing and Bio-Sensing Research, 13, 9-16. https://doi.org/10.1016/j.sbsr.2017.01.004

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