Linda B. Neubrand, Xavier Attendu and Ton G. van Leeuwen
Article (2025)
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Abstract
In this study, we aim to validate the analytical Cramer-Rao lower bound (CRLB) equation for determining attenuation coefficients using a 1310 nm Optical Coherence Tomography (OCT) system. Our experimental results successfully confirm the validity of the equation, achieving unprecedented precision with a standard deviation below 0.01 mm⁻¹ for intralipid samples. Furthermore, we introduce a systematic framework for attaining high precision in OCT attenuation measurements.
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| Department: | Department of Engineering Physics |
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| Research Center: | COPL - Centre d'optique, photonique et laser |
| Funders: | Dutch Research Council (NWO) |
| PolyPublie URL: | https://publications.polymtl.ca/62050/ |
| Journal Title: | Journal of biophotonics (vol. 18, no. 3) |
| DOI: | 10.1002/jbio.202400395 |
| Official URL: | https://doi.org/10.1002/jbio.202400395 |
| Date Deposited: | 21 Jan 2025 09:42 |
| Last Modified: | 08 Jan 2026 09:08 |
| Cite in APA 7: | Neubrand, L. B., Attendu, X., & van Leeuwen, T. G. (2025). Achieving high-precision attenuation coefficient measurement in optical coherence tomography. Journal of biophotonics, 18(3), e202400395 (14 pages). https://doi.org/10.1002/jbio.202400395 |
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