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Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

Robin Guay-Lord, Xavier Attendu, Kristen L. Lurie, Lucas Majeau, Nicolas Godbout, Audrey K. Ellerbee Bowden, Mathias Strupler and Caroline Boudoux

Article (2016)

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This work demonstrates the combination of optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a double-clad optical fiber coupler. The single-mode core of the fiber is used for OCT imaging, while the inner cladding of the double-clad fiber provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of the sample morphology with OCT, enhanced with complementary molecular information contained in the hyperspectral image. The HSI data can be used to highlight the presence of specific molecules with characteristic absorption peaks or to produce true color images overlaid on the OCT volume for improved tissue identification by the clinician. Such a system could be implemented in a number of clinical endoscopic applications and could improve the current practice in tissue characterization, diagnosis, and surgical guidance.

Uncontrolled Keywords

Humans; Imaging, Three-Dimensional/*methods; *Optical Fibers; Skin/diagnostic imaging; Spectrum Analysis/*methods; Tomography, Optical Coherence/*methods

Subjects: 1900 Biomedical engineering > 1900 Biomedical engineering
3100 Physics > 3110 Optics (see also Photon devices, 2505)
Department: Department of Engineering Physics
Funders: Canada Foundation for Innovation (CFI) / Fondation canadienne pour l'innovation (FCI), CRSNG/NSERC, Biomedical Sciences and Technologies Research Centre/Centre de recherche en sciences et technologies biomédicales (GRSTB), National Science Foundation Graduate Research Fellowship (NSFGRF)
PolyPublie URL: https://publications.polymtl.ca/4909/
Journal Title: Journal of Biomedical Optics (vol. 21, no. 11)
Publisher: SPIE
DOI: 10.1117/1.jbo.21.11.116008
Official URL: https://doi.org/10.1117/1.jbo.21.11.116008
Date Deposited: 30 Sep 2021 15:44
Last Modified: 17 May 2023 05:55
Cite in APA 7: Guay-Lord, R., Attendu, X., Lurie, K. L., Majeau, L., Godbout, N., Ellerbee Bowden, A. K., Strupler, M., & Boudoux, C. (2016). Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler. Journal of Biomedical Optics, 21(11), 116008-1-116008-6. https://doi.org/10.1117/1.jbo.21.11.116008


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